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Greg Arling, PhD

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
garling@iupui.edu

 

Dr. Arling’s research interests are in health care quality assessment, evaluation, and policy analysis. Much of his research has been with elderly populations in long-term care settings where he has helped develop comprehensive measures of care quality, assessed the accuracy and effectiveness of these measures, and applied them to quality improvement, public reporting and pay-for-performance. Dr. Arling has studied transitions between care settings, such as hospital, nursing home, and community care. Currently, he is Principal Investigator of two Research and Demonstration grants from the Agency for Health Care Research and Quality: Evaluating a Comprehensive State-Level Model to Improve Nursing Home Quality, and a Study of a State-Level Model for Transitioning Nursing Home Residents to the Community.

Matthew J. Bair, MD, MS

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
mbair@iupui.edu

 

Dr. Bair’s research focuses on understanding the interface between affective disorders (e.g. depression and anxiety) and chronic pain and developing strategies to improve pain management in the primary care setting. Dr. Bair’s major educational foci are teaching implementation research methods and evidence-based medicine to medical residents, fellows, and IUPUI junior faculty.

 

Dawn M. Bravata, MD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
  • Clinical Coordinator, VA HSR&D Stroke Quality Enhancement Research Initiative (QUERI)
dawn.bravata2@va.gov

 

Dr. Bravata conducts health services research in cerebrovascular disease. The fundamental goal of her research is to improve the quality of care for stroke patients and others with cerebrovascular disease. She is interested in three topics within this larger domain: measurement of quality of care received by patients with stroke and transient ischemic attack, effectiveness and implementation of interventions for patients with acute ischemic stroke and transient ischemic attack, and the identification and treatment of medical co-morbidities in patients with cerebrovascular disease.

 

Paul Biondich, MD, MS

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Pediatrics, Indiana University School of Medicine
pbiondic@regenstrief.org

 

Dr. Biondich’s research interests include clinical decision support systems and the use of large scale, consolidated electronic health information infrastructures in this regard. His focus is in resource poor environments throughout the world, currently leading the OpenMRS initiative, and helping develop national health information exchanges for Rwanda and other African countries. He also is the director of clinical informatics for AMPATH in Western Kenya, and the director of the Fogarty East African Health Informatics Fellowship program.

Malaz Boustani, MD, MPH

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Associate Director, Indiana University Center for Aging Research
mboustan@iupui.edu

 

Dr. Boustani is interested in enhancing the quality of the current health care system to accommodate the needs of patients with cognitive impairment in general and those with dementia in particular. He is working on the development of a multifaceted dementia care system across various health care settings including ambulatory, primary and secondary care, hospital environment, and long-term care facilities. He is involved in various large projects aimed at identifying the barriers to development of an enhanced system in primary care (PREVENT, PRISM-PC, and I-NEEDS studies), the hospital (PMD, e-CHAMP, 3Ds, and POCD projects), and in long-term care (ALFA and Dementia Care studies).

 

Christopher M. Callahan, MD

  • Director of Aging Research and Research Scientist, Regenstrief Institute, Inc.
  • Cornelius and Yvonne Pettinga Professor in Aging Research, Professor of Medicine, Indiana University School of Medicine
  • Director, Indiana University Center for Aging Research
ccallaha@iupui.edu

 

Dr. Callahan’s research seeks to improve the outcomes of care for older adults with late life depression and dementia. His work explores innovative models of care that support the generalist physician in their day-to-day provision of health care for older adults. These new models of care focus on collaboration between health care providers, patients, and family as well as across the continuum of care with an emphasis on the application of information technology.

Noll L. Campbell, PharmD

  • Research Scientist, Regenstrief Institute, Inc.
  • Research Assistant Professor, Department of Pharmacy Practice, Purdue University College of Pharmacy
  • Center Scientist, Indiana University Center for Aging Research
campbenl@regenstrief.org

 

Dr. Campbell’s interest is in medication management of older adults with cognitive impairment. As an aging brain pharmacoepidemiologist he is most interested in the impact medications may have on the development or progression of cognitive dysfunction. This work extends to both the acute care (Pharmacologic Management of Delirium, PMD study) and ambulatory environments (COMET-AD, comparative effectiveness study in Alzheimer’s Disease). Additionally, he is interested in improving both appropriateness of and adherence to medication use in older adults.

Clint Cary, MD, MPH

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor, Department of Urology, Indiana University School of Medicine
kcary@iupui.edu

 

Dr. Cary completed his urology residency at Indiana University and then went on to complete a two year urologic oncology fellowship at the University of California, San Francisco. In addition to his fellowship, he completed a Master of Public Health Degree from U.C. Berkeley with a concentration in epidemiology. His clinical interest is in urologic oncology. His research efforts will focus on health services and outcomes research in testis, bladder, and prostate cancer.

 

Daniel O. Clark, PhD

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
dclark@gorge.net

 

Dr. Clark’s interests are in the design, evaluation, and translation of primary care-based interventions to support physical activity and self-management of chronic disease. Dr. Clark is co-director of the IU-Roybal Center for Translation Research on Chronic Disease Self-Management Among Vulnerable Older Adults.

Teresa M. Damush, PhD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Associate Research Professor in Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
  • Implementation Research Coordinator, VA HSR&D Stroke Quality Enhancement Research Initiative (QUERI)
  • Center Scientist, Indiana University Center for Aging Research
  • Affiliated Scientist, Center for Enhancing Quality of Life in Chronic Illness, Indiana University School of Nursing
Teresa.Damush@va.gov

 

Dr. Damush is a social psychologist specializing in health psychology. As the Implementation Research Coordinator for the Stroke QUERI Center, Dr. Damush's research focuses on implementing evidence-based practices for stroke survivors and caregivers. She collaborates with colleagues on designing and evaluating system interventions in the delivery of evidence-based practices. She has funding from of the Department of Veterans Affairs to adapt existing evidence-based tools for secondary stroke prevention from hospital discharge to the veterans' homes. In addition, Dr. Damush continues to design and evaluate disease self-management programs for chronic medical conditions including musculoskeletal pain and stroke.

Paul R. Dexter, MD

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Clinical Medicine, Indiana University School of Medicine
prdexter@regenstrief.org

 

Dr. Dexter has been a research scientist at Regenstrief Institute for the last twenty years with a focus on adapting Regenstrief’s information systems for both clinical and research purposes. He is the Chief Medical Information Officer (CMIO) and Director of Clinical Effectiveness of Eskenazi Health, helping shape the Gopher physician order entry system.  He has conducted multiple trials related to computerized clinical reminder systems. He has helped implement a robust research IT infrastructure at Regenstrief Institute that includes tools related to decision support, natural language processing, and the efficient performance of identified and de-identified data queries.

Brian E. Dixon, MPA, PhD, FHIMSS

  • Research Scientist, Regenstrief Institute, Inc.
  • Center for Biomedical Informatics and Indiana University Center for Health Services and Outcomes Research
  • Assistant Professor of Health Informatics, Indiana University School of Informatics
  • Investigator in Residence, VA Health Services Research and DevelopmentCenter for Health Information and Communication, Richard L. Roudebush VA Medical Center
bedixon@regenstrief.org

 

Dr. Dixon’s research focuses on developing and evaluating innovative technologies and processes for managing knowledge regarding individual patients and populations. His recent work has involved leveraging health information exchange (HIE) to enable secondary use of clinical and administrative data to improve public health surveillance, continuity of care for veterans, the determination of disability, and clinical decision support. He has further played a key role in projects that support interoperability standards, including the LOINC® terminology, automated reporting of surveillance data to public health, and big data analytics in health care. Dr. Dixon’s teaching duties include courses on public health informatics, informatics evaluation methods, health information exchange, and big data/health analytics.

Stephen M. Downs, MD

  • Jean and Jerry Bepko Professor of Pediatrics
  • Director of Children’s Health Services Research
  • Director of General and Community Pediatrics

smdowns@iu.edu

Dr. Downs’s research interests include computer-based decision support systems for primary care, expected utility theory, decision analysis and cost-effectiveness analysis.

Jon Duke, MD, MS

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Medicine, Indiana University School of Medicine
jonduke@regenstrief.org

 

Dr. Duke currently serves as Director of Regenstrief Institute’s Drug Safety Informatics Lab and as the Institute’s Chief Innovation Officer. He also leads the Merck-Regenstrief Program in Healthcare Research and Innovation.  Dr. Duke’s primary research focus is on applying big data and human computer interaction to identifying adverse drug event risk and effectively communicating this information through clinical decision support and advanced product labeling. His other area of research is in EHR design and innovation, including the integration of natural language processing in the clinical workflow to improve the quality and efficiency of care. Dr. Duke is fluent in Japanese and has done work with the medical informatics community in Japan. He continues to see patients as a practicing internist.

John T. Finnell, MD, MSc

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Emergency Medicine, Indiana University
jtfinnell@regenstrief.org

 

Dr. Finnell's interests lie in the application of medical informatics to the practice of emergency medicine. His current work involves implementing public health measures during an emergency department visit. He has implemented a vaccination program that ensures eligible patients access to influenza and pneumococcal vaccines during their emergency encounter. Additional work involves providing electronic healthcare data to out-of-hospital personnel: Indianapolis Motor Speedway and to the EMS providers of Marion and Hamilton counties - one of the first such systems in the nation.

Richard M. Frankel, PhD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Professor of Medicine, Indiana University School of Medicine
  • Associate Director, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
  • Director, Palliative Care Research and Education Program, Indiana University Melvin and Bren Simon Cancer Center
rfrankel@iupui.edu

 

Dr. Frankel’s research interests include organizational culture change, quality and safety in healthcare, the effects of communication on processes and outcomes of care and conversations at the end of life. He is the statewide competency director for the IU School of Medicine’s professionalism competency. Dr. Frankel’s educational interests include interventions with physicians and patients to improve communication about chronic pain, faculty development with specific emphases on helping new faculty succeed, teaching humanism at the bedside, and implementing and evaluating experiential and other interactive learning formats that incorporate personal awareness and mindfulness.

Shaun Grannis, MD, MS, FAAFP

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Family Medicine, Indiana University School of Medicine
sgrannis@regenstrief.org

 

Dr. Grannis collaborates closely with national and international public health stakeholders to advance the technical infrastructure and data-sharing capabilities. He is a member of World Health Organization (WHO) Collaborating Center for the Design, Application, and Research of Medical Information Systems, where he provides consultancy on issues related to health information system identity management and implementing automated patient record matching strategies. Dr. Grannis’s analysis of an automated regional electronic laboratory reporting system revealed substantial increases in the capture rates for diseases of public health significance when compared to manual, paper-based procedures. He directed an initiative integrating data flows from over 120 hospitals across the state of Indiana for use in public health disease surveillance. For the last 5 years this system has received real-time data from hospitals amounting to more than 2 million transactions per year, and has detected public health outbreaks of gastrointestinal illness, carbon monoxide poisoning, and other events of interest to public health. Most recently, this system was leveraged to monitor H1N1 influenza disease burden across the state of Indiana. As co-chair of the U.S. Health Information Technology Standards Panel (HITSP) Population Health technical work group, Dr. Grannis helped lead development of technical Interoperability Specifications for nationally recognized public health IT use cases. Dr. Grannis also serves as the Director of the Indiana Center of Excellence in Public Health Informatics, which recognizes that public health practice is driven by a wide variety of data types, data sources, and data management techniques.

David A. Haggstrom, MD, MAS

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
  • Associate Member, Melvin and Bren Simon Indiana University Cancer Center
dahaggst@iupui.edu

 

Dr. Haggstrom is a cancer health services researcher broadly interested in the measurement and improvement of the quality of health care delivery across the cancer continuum. In addition to implementation science, Dr. Haggstrom has a special interest in medical informatics, including personal health records and health information exchange. Dr. Haggstrom has assessed the quality of cancer treatment and surveillance using large datasets, including VA cancer registry and SEER-Medicare data. With support from the VA and Livestrong Foundation, Dr. Haggstrom has studied the influence of patient, provider, and organizational factors upon the quality of survivorship care among colorectal cancer survivors. He has also developed a personal health record to meet the patient-centered needs of cancer survivors, and performed qualitative and quantitative evaluation of the tool. Currently, Dr. Haggstrom is conducting an evaluation of health information exchange between the VA and IHIE in order to better understand the impact upon underuse, costs, and overuse.

Hugh C. Hendrie, MB, ChB, DSc

  • Research Scientist, Regenstrief Institute, Inc.
  • Professor of Psychiatry, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
hhendri@iupui.edu

 

Dr. Hendrie is co-principal investigator of a multi-disciplinary group of researchers conducting international comparative studies of dementia and Alzheimer’s disease in Nigeria and the United States supported by the National Institute on Aging and a co-investigator on an NIA-supported study investigating the association between selenium and cognitive decline in Chinese villagers. He also chaired a National Institutes of Health committee on factors influencing cognitive and emotional health and was on the steering committee of the Center for Disease Control/Alzheimer’s Association Healthy Brain Initiative. Dr. Hendrie collaborates on intervention trials for the treatment of depression and dementia in primary care and in late life chronic mental illnesses. He is currently on the executive committee of the NIH Toolbox project, whose goal is to create brief, comprehensive assessment tools in the areas of cognition, emotion, motor and sensory function across the life span.

Siu L. Hui, PhD

  • Research Scientist, Regenstrief Institute, Inc.
  • Professor of Medicine, Indiana University School of Medicine
  • Director of Biostatistics, Indiana University Center for Aging Research
shui@iupui.edu

 

Dr. Hui, the senior biostatistician at the Institute, actively collaborates with Institute scientists in both the Medical Informatics and Health Services areas and conducts her own research. She participates in many projects involved with aging, including osteoporosis, menopause, dementia and cardiovascular disease. Her research interest is in the development of statistical methods and the application of innovative techniques to address biomedical and health services research questions. Statistical areas include missing and longitudinal data, statistical modeling, and measurement errors.

Timothy D. Imler, M.D., M.S.

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine
timler@iu.edu.

 

Dr. Imler is trained in Internal Medicine, Medical Informatics, and Gastroenterology. His clinical interests are general gastroenterology, colorectal cancer screening and surveillance, and quality improvement in endoscopy. Dr. Imler’s research interests are in combining Medical Informatics tools within Gastroenterology to improve patient outcomes.

Dr. Imler received his medical degree from Case Western Reserve University School of Medicine in Cleveland, Ohio. He completed his internal medicine residency, served as Chief Resident, and completed a GI fellowship at Indiana University School of Medicine. He completed a Master’s degree in Health Informatics from Indiana University and a Medical Informatics fellowship through the Regenstrief Institute. He is an Assistant Professor of Medicine at Indiana University School of Medicine division of Gastroenterology and Hepatology.

Thomas F. Imperiale, MD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Professor of Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
timperia@iupui.edu

 

Dr. Imperiale’s primary research interests include tailoring screening for colorectal cancer based on individual patient risk, and using quantitative research methods to assess existing and new technologies for digestive diseases.

Thomas S. Inui, ScM, MD, MACP

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Joe and Sarah Ellen Mamlin Professor of Global Health Research, Indiana University School of Medicine
  • Director of Research, Indiana University Center for Global Health
  • Director (North America), AMPATH Research Network
tinui@iupui.edu

 

A primary care physician, educator, and researcher, Dr. Inui’s special emphases in teaching and research have included physician/patient communication, health promotion and disease prevention, chronic disease management, the social context of medicine, and medical humanities. Since October 2010, he has served as Co-Director of Research for the IU-Kenya AMPATH Program.

Shelley A. Johns, PsyD, ABPP

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Assistant Professor of Medicine, Indiana University School of Medicine
  • Board Certified Clinical Health Psychologist, Palliative Care Program, Wishard Health Services
sheljohn@iupui.edu

 

Dr. Johns’ research focus is on expanding treatment options for symptom management for adults with cancer and other chronic medical conditions. She is interested in the application of mindfulness- and acceptance-based behavioral interventions in health care settings, the development and testing of dignity-enhancing interventions as death draws near, and building the science of palliative and end-of-life care across the lifespan.

Jacob Kean, PhD, CCC-SLP

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Assistant Research Professor, Department of Physical Medicine and Rehabilitation, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
jakean@indiana.edu

 

Dr. Kean's research interests include telehealth and telemedicine, rehabilitation, and the development and implementation of clinical and outcomes assessment, focusing on item response theory and other modeling approaches to inference. Dr. Kean's education interests include assessment design and program evaluation in higher education, including simulation-based assessment.

Babar Khan, MD, MS

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Aging Research
  • Assistant Professor of Medicine, Indiana University School of Medicine; Division of Pulmonary/Critical Care
bakhan@iupui.edu

 

Dr. Khan's research is at the critical intersection of acute illness and aging brain. He is a patient oriented-translational/clinical researcher with a principal focus on developing a biomarker profile among delirious patients in the intensive care unit to predict their long term cognitive, physical and psychological morbidity. In addition, he directs the "Critical Care Recovery Center- CCRC", located at Wishard Health Services. CCRC is an innovative center balancing research and clinical services that sought to implement the advances in the science of "Post-ICU syndrome" for expeditious recovery and rehabilitation of ICU survivors.

Kurt Kroenke, MD

  • Director of Education and Training Programs, Regenstrief Institute, Inc.
  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes
  • Professor of Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
kkroenke@regenstrief.org

 

Dr. Kroenke focuses his clinical research on the optimal evaluation and management of common symptoms such as pain, fatigue, and other physical complaints. He also conducts research on depression, anxiety and other mental disorders in primary care. His methodological expertise includes clinical trials, development of patient-reported outcome measures, clinical epidemiology, and health services research. He is Director of the Research Education and Career Development program for the Indiana Clinical and Translational Sciences Institute (CTSI). He is also Director of the Clinical Investigation and Translational research Education (CITE) and the Master of Science in Clinical Research programs, which offers training and educational opportunities for fellows and junior faculty from numerous disciplines.

Michael LaMantia, MD, MPH

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Medicine, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
malamant@iupui.edu

 

Dr. LaMantia’s research focuses on the coordination of care for older, vulnerable patients as they transition across sites of healthcare delivery. He has a particular interest in the care of seniors in the emergency department and especially the care provided to seniors with delirium and dementia.

Xiaochun Li, PhD

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor, Department of Biostatistics, Indiana University School of Medicine, Indiana University Richard M. Fairbanks School of Public Health
xiaochun@iupui.edu

 

Dr. Li's current primary research interest is in developing statistical methods for the analysis of observational data, mostly from population-level electronic medical records. She has conducted research in statistical methods dealing with confounding with missing data. Dr. Li has been involved in research projects in pharmacoepidemiology for drug safety and public health and has extensive experience working with a team of medical researchers, biostatisticians and data managers on various database and clinical studies. She is the project lead and co-lead of two industry funded projects on statistical methodology of confounding control and characterization of hypertension patients and management as well as the Core Leader for the Biostatistics Core of the 2012 Merck-Regenstrief collaboration. Other interests include statistical computing, non- and semi-parametric regression, clinical trials and bioinformatics.

Debra K. Litzelman, MA, MD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Professor of Medicine and Associate Dean for Research in Medical Education, Indiana University School of Medicine
  • Director of Education, Indiana University Center for Global Health
dklitzel@iupui.edu

 

Dr. Litzelman's primary interests are in interprofessional education, organizational change strategies, and clinical teaching skills development for residents and faculty. She is widely published in the areas of curricular innovations, shaping the informal curriculum of academic health centers, and clinical teaching effectiveness. Dr. Litzelman has been recognized for implementing various innovative, online assessment tools and programs, including an online evaluation system for statewide undergraduate medical courses and instructors and disseminating and tracking student performance as they progress through an integrated four-year competency-based curriculum. She is currently the principal investigator on IU School of Medicine’s Behavioral and Social Science Integrated Curriculum Program. Dr. Litzelman is also the lead investigator for the Education and Training Core for the CMS funded grant to disseminate the Aging Brain Care Program.

Burke Mamlin, MD

  • Research Scientist, Regenstrief Institute, Inc.
  • Clinical Associate Professor of Medicine, Indiana University School of Medicine
bmamlin@regenstrief.org

 

Dr. Mamlin has been involved in the design and development of computer applications for medicine at Regenstrief Institute for over three decades with a focus on physician order entry. He helped create the Medical Gopher Order Entry system and helped lead the development of it's successor, G3. He has extensive programming experience and continues to practice medicine as a general internist while mentoring informatics fellows. Dr. Mamlin is applying his experience at Regenstrief to the design and development of an electronic medical record system for developing counties (OpenMRS.org). OpenMRS is used in dozens of countries, including the treatment and prevention of HIV/AIDS in Sub-Saharan Africa as part of Indiana University’s Kenya Program

Douglas K. Martin, MD

  • Research Scientist, Regenstrief Center for Biomedical Informatics, Regenstrief Institute, Inc.
  • Professor of Clinical Medicine, Indiana University School of Medicine
dkmartin@regenstrief.org

 

Dr. Martin specializes in component-based application architectures, clinical data modeling, clinical vocabularies, clinical repository architecture, system integration, healthcare data standards, and clinical decision support systems. He is the principal architect of the CareWeb Framework, a web-hosted, component-based, open-architecture infrastructure that permits the dynamic construction of highly configurable clinical applications using a best-of-breed approach.

Marianne S. Matthias, PhD

  • Research Scientist, Regenstrief Institute, Inc. andIndiana University Center for Health Services and Outcomes Research
  • Adjunct Assistant Professor, Department of Communication Studies, Indiana University
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
mmatthia@iupui.edu

 

Dr. Matthias’ research interests include relationship-centered care and its effect on health care processes and outcomes, patient-provider communication, patient activation, and clinical decision making. Dr. Matthias is particularly interested in communication in chronic pain care and severe mental illness.

Edward J. Miech, EdD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Assistant Professor, Department of Emergency Medicine, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
  • Special Graduate Faculty Appointment, Purdue University
edward.miech@va.gov

 

Dr. Miech’s expertise is in program evaluation, assessment, educational theory, and mixed methods. Dr. Miech has been a co-investigator on several VA HSR&D studies and is principal investigator on a three-year, mixed methods study of the impact of context on the efforts of twelve VA sites to improve inpatient stroke care. He is also a faculty member of VA-CASE, the Veterans Engineering Resource Center based in Indianapolis and Detroit. In this capacity, he serves on planning committees for VA Systems Redesign initiatives – including collaboratives at the local, regional, and national levels – and helps plan and conduct program evaluations.

Douglas K. Miller, MD

  • Research Scientist, Regenstrief Institute, Inc.
  • Professor of Medicine, Indiana University School of Medicine
  • Richard M. Fairbanks Professor of Aging Research and Associate Director, Indiana University Center for Aging Research
dokmille@iupui.edu

 

Dr. Miller's interests include the causes, prevention, and remediation of frailty and decline of self-care functioning in late, middle-aged, and older persons, especially in socially vulnerable urban African-Americans. Dr. Miller is also interested in improving community-academic partnerships, community-engaged research, and the care of older patients visiting emergency departments.

Michael (Mick) D. Murray, PharmD, PhD

  • Executive Director, Regenstrief Center for Healthcare Effectiveness Research
  • Director, Regenstrief Institute Data Core, Regenstrief Institute, Inc.
  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Distinguished Professor of Pharmacy and Endowed Chair of Medication Safety, Purdue University College of Pharmacy
  • Adjunct Professor, Division of General Internal Medicine and Geriatrics, Indiana University School of Medicine
mdmurray@regenstrief.org

 

Dr. Murray’s research interests include developing pharmacy services to improve drug therapy in older adults with chronic disorders, medication safety, improving the quality of health of low-income minority people, and pharmacoepidemiology using large population computer databases.

Alissa L. Russ, PhD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Adjunct Assistant Professor, College of Pharmacy, Purdue University
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
alissa.russ@va.gov

 

Dr. Russ is a human factors engineering specialist with interests in clinical information systems and medication safety. Her primary research interests include computerized provider order entry (CPOE); computerized decision support for medications (e.g., drug-drug interaction alerts); and understanding how informatics can be improved to enhance patient safety.

Greg A. Sachs, MD

  • Research Scientist, Regenstrief Institute, Inc.
  • Chief, Division of General Internal Medicine and Geriatrics, Department of Medicine, and Professor of Medicine, Indiana University School of Medicine
  • Center Scientist, IU Center for Aging Research
sachsg@iupui.edu

 

Dr. Sachs’s research and writing focus on ethical issues in geriatrics, especially those involving people with dementia. Specific areas included in Dr. Sachs’s work are the ethics of decision making for the care of people with dementia, palliative care in dementia, and the ethics of dementia research. Dr. Sachs has been the recipient of grants from NIA, AHRQ, and the leading foundations funding research in geriatrics, ethics, or palliative care.

Titus K. Schleyer, DMD, PhD

  • Research Scientist, Clem McDonald Professor of Biomedical Informatics, Director, Center for Biomedical Informatics, Regenstrief Institute, Inc.
  • Professor of Medicine, Department of Medicine, Indiana University School of Medicine
schleyer@regenstrief.org

 

Dr. Schleyer has been active in informatics research since 1989, conducting seminal research on electronic health records, Internet applications, and workflow and human-computer interaction in dentistry. In 2009, Dr. Schleyer was elected to the American College of Medical Informatics, a select group of individuals who have made significant and sustained contributions to the field of biomedical informatics. Dr. Schleyer also serves as director of the biomedical informatics core of the Indiana Clinical and Translational Sciences Institute. More information about Dr. Schleyer is available at http://about.me/titusschleyer  Dr. Schleyer tweets about biomedical informatics at @titusschleyer and writes a blog on biomedical informatics and health information technology.

Linas Simonaitis, MD

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Clinical Medicine, Indiana University School of Medicine
lsimonai@regenstrief.org

 

Dr. Simonaitis’ chief interest is the Knowledge Engineering which is necessary in order to enable effective Clinical Decision Support, Quality Measurement, and Research Queries. Within Knowledge Engineering, he is focused on the use of Vocabulary Standards: enabling clinicians to enter orders and other data linked to standard vocabularies; the effective display to clinicians of concepts obtained from standard vocabularies; mapping concepts between disparate vocabularies; creating categories and hierarchies of knowledge; and sharing knowledge between different institutions. To date, his work has emphasized the two domains of drugs and diseases.

Blaine Y. Takesue, MD

  • Research Scientist, Regenstrief Institute, Inc.,
  • Clinical Assistant Professor of Medicine, Indiana University School of Medicine
btakesue@iupui.edu

 

Dr. Takesue is one of the clinical leaders in the re-engineering of the Regenstrief Gopher computer physician order entry system. The new system is designed by providers for providers using common internet paradigms. The design goal is to create a platform which will allow providers to care for patients safely, allow for innovation in system design as well as patient care, and facilitate continued clinical and informatics research. Included in Dr. Takesue’s research interests is tracking patient healthcare system preferences using the Indiana Network for Patient Care.

William M. Tierney, MD

  • President and CEO of Regenstrief Institute, Inc.
  • Chancellor's Professor of Medicine and Associate Dean for Clinical Effectiveness Research, Indiana University School of Medicine
wtierney@iupui.edu

 

William Tierney, MD is the President and CEO of the Regenstrief Institute, Inc. In 2010, Dr. Tierney became only the second person to hold this role at the Regenstrief Institute which is the oldest and most productive research organization in the U.S. focusing on enhancing health care delivery systems to improve the quality, effectiveness, and efficiency of care. He is also Chancellor’s Professor at the Indiana University School of Medicine where he also holds the Sam Regenstrief Chair in Health Services Research and serves as Associate Dean for Clinical Effectiveness Research. Dr. Tierney’s research focuses on implementing electronic health record systems (EHRs) in hospital and outpatient venues in Indiana and in East Africa, where his team of developers implemented sub-Saharan African’s first ambulatory EHR. With the engagement of EHR developers from the Regenstrief Institute, Partners in Health, and the Research Council of South Africa, this system has grown into OpenMRS which Tierney and his colleagues have implemented in more than 50 clinics and hospitals in Kenya, Tanzania, and Uganda and which, through the OpenMRS Consortium, has been employed in more than 40 countries, mostly in the developing world. In the 1980s, Dr. Tierney helped design, deploy, and study one of the first computer-based provider order-entry systems in the U.S. in Wishard Health Services where it and other computer-based tools have enhanced the quality and efficiency of health care. A former Editor in Chief of Medical Care and the Journal of General Internal Medicine, he has published more than 280 peer-reviewed journal articles focusing on biomedical informatics, health services research, and clinical epidemiology. Dr. Tierney is a member of the Institute of Medicine, a Master of the American College of Physicians, a Fellow of the American College of Medical Informatics, and a former President of the Society of General Internal Medicine. Dr. Tierney tweets and blogs about biomedical informatics at @wtierney51 and Bill Tierney’s blog, respectively.

Alexia M. Torke, MD, MS

  • Research Scientist, Regenstrief Institute; Associate Professor of Medicine, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
  • Director, Fairbanks Fellowship in Medical Ethics
atorke@iupui.edu

 

Dr. Torke is interested in the ethical and communication aspects of medical decision making. She has conducted research on patients’ preferences for end-of-life care and currently focuses on the topic of surrogate decision making – how family members and others make major decisions for patients with dementia, delirium or other conditions that impair cognitive function. She has designed and evaluated curricula regarding end-of-life care and clinical ethics for medical students, residents and fellows.

Wanzhu Tu, PhD

  • Research Scientist, Regenstrief Institute Inc.,
  • Professor of Biostatistics, Department of Biostatistics, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
wtu1@iupui.edu

 

Dr. Tu’s primary research interest is the development of new analytical methods for clinical and epidemiological studies. His current research activities involve statistical modeling assessing hypertension risks, and the analysis of health service outcome data.

Kathleen Unroe, MD, MHA

  • Research Scientist, Regenstrief Institute
  • Assistant Professor of Medicine, Indiana University School of Medicine
  • Center Scientist, Indiana University Center for Aging Research
kunroe@iupui.edu

 

Dr. Unroe is focused on health policy relevant research in long term care, including the use of palliative care and hospice in this setting, transitions of care, quality of medical care in nursing homes, and staffing models in long term care. She provides clinical care in nursing homes.

Daniel J. Vreeman, PT, DPT, MSc

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Research Professor, Indiana University School of Medicine
dvreeman@regenstrief.org

 

Dr. Daniel Vreeman is an Assistant Research Professor at the Indiana University School of Medicine and a Research Scientist at the Regenstrief Institute, Inc. Dr. Vreeman’s primary research focus is on the role of standardized clinical vocabularies and standards to support electronic health information exchange. As Associate Director for Terminology Services at Regenstrief he directs the development of LOINC, an international standard for laboratory and clinical observations, and provides leadership to the terminology services that undergird the Indiana Network for Patient Care, a regional health information exchange in central Indiana. Dr. Vreeman also teaches medical informatics at Indiana University. More information on Dr. Vreeman's research and professional interests can be found at: http://danielvreeman.com

 

 

Michael Weiner, MD, MPH

  • Director of Health Services Research and Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Director, Indiana University Center for Health Services and Outcomes Research
  • Principal Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
mw@cogit.net

 

Dr. Weiner's professional interests are health services research, geriatrics, and health informatics. At IU Geriatrics, he founded the gero-informatics program, which under his leadership focused on leveraging health information technologies to improve the care of older adults. His clinical and health-services research is focused on measuring and improving the quality, coordination, and delivery of health services for older adults. He also studies the effects of health information and information technology on physicians' practices and patients' outcomes. Dr. Weiner has conducted studies of specialty referral, patient-physician videoconferencing, and other forms of telecommunication to improve healthcare. Current research includes development, implementation, and study of information systems to promote clinical handoffs, management of medications, patient-centered geriatrics care, and clinical decision support.

Martin C. Were, MD, MS

  • Research Scientist, Regenstrief Institute, Inc.
  • Assistant Professor of Medicine, Indiana University School of Medicine
mwere@regenstrief.org

 

Dr. Were’s work focuses on developing, implementing, and evaluating provider-facing mHealth and computerized clinical decision support systems for resource-limited settings. In the U.S., he leads projects that use health information exchange infrastructure to improve transition of care from inpatient to outpatient settings and to automate the patient-provider attribution process.

Dr. Were is the Chief Medical Information officer for the AMPATH program in Western Kenya, a lead for a new Masters and PhD program in Health Informatics Program at Moi University (Kenya), and is on the Board of Scientific Counselors at Lister Hill Center of NLM at the National Institutes of Health (USA). He holds an AB degree in Biochemistry from Harvard College, and an MD degree from Harvard Medical School. He is a board-certified Internal Medicine physician trained at Brigham and Women’s Hospital and Harvard Medical School.

Linda S. Williams, MD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Professor of Neurology, Indiana University School of Medicine
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
  • Research Coordinator, VA HSR&D Stroke Quality Enhancement Research Initiative (QUERI)
linda.williams6@va.gov

 

Dr. Williams' research focuses on improving outcomes for patients with stroke. Her primary research interests include investigating the impact of post-stroke depression; conducting effectiveness trials to improve stroke outcomes and implementing best evidence to systematically improve the quality of stroke care.

Alan J. Zillich, PharmD

  • Research Scientist, Regenstrief Institute, Inc. and Indiana University Center for Health Services and Outcomes Research
  • Associate Professor of Pharmacy Practice, Purdue University College of Pharmacy
  • Core Investigator, VA Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center
azillich@purdue.edu

 

Dr. Zillich’s research interests involve the roles of professional collaborative relationships between pharmacists and other health care providers; the effectiveness of pharmacy-based services on improved medication prescribing, patient safety, and patient health outcomes; and methods to improve prescribing and utilization of medications through systems redesign and health informatics.

Malaz Boustani, MD, MPH

  • Research Scientist, Regenstrief Institute, Inc.
  • Associate Professor of Medicine, Indiana University School of Medicine
  • Associate Director, Indiana University Center for Aging Research
mboustan@iupui.edu

 

Dr. Boustani is interested in enhancing the quality of the current health care system to accommodate the needs of patients with cognitive impairment in general and those with dementia in particular. He is working on the development of a multifaceted dementia care system across various health care settings including ambulatory, primary and secondary care, hospital environment, and long-term care facilities. He is involved in various large projects aimed at identifying the barriers to development of an enhanced system in primary care (PREVENT, PRISM-PC, and I-NEEDS studies), the hospital (PMD, e-CHAMP, 3Ds, and POCD projects), and in long-term care (ALFA and Dementia Care studies).