Regenstrief Institute, Inc

Thomas S. Inui, ScM, MD, President and CEO of Regenstrief Institute, Inc. and Sam Regenstrief Professor of Health Services Research; Professor of Medicine and Associate Dean for Health Care Research, Indiana University School of Medicine.

Health Services Research/IUCHSOR

Bradley N. Doebbeling, MD, MSc, FACP, Associate Director and Research Scientist, Regenstrief Institute, Inc.; Director, Indiana University Center on Health Services and Outcomes Research and VA Health Services Research and Development (HSR&D) Center of Excellence on Implementing Evidence-based Practices, Richard L. Roudebush VA Medical Center; Department of Medicine Professor of Health Services Research and Medicine, Indiana University School of Medicine.

Dr. Doebbeling, a nationally recognized health care epidemiologist, health services researcher, and mentor, directs the Institute’s Health Services Research Program. His center focuses on improving healthcare through discovery, evaluation, implementation, and sustained adoption of evidence-based clinical and management practices. Dr. Doebbeling's research focuses on identifying environmental, organizational, provider and patient factors influencing the effectiveness of systems interventions, such as implementing decision support, to improve healthcare. His methodologic work has defined new approaches to benchmark performance and identify determinants of program effectiveness. His research is interdisciplinary and cross-cutting in the areas of the prevention and management of antimicrobial resistance and patient safety, mental health, cancer and other chronic conditions. Dr. Doebbeling also serves as Associate Director for the NIH K30 Clinical Investigator Training Enhancement (CITE) Program.

Medical Informatics

J. Marc Overhage, MD, PhD, is Director of Medical Informatics and Research Scientist, Regenstrief Institute, Inc., President and CEO of the Indiana Health Information Exchange, Regenstrief Professor of Medical Informatics and Professor of Medicine at Indiana University School of Medicine.

Dr. Overhage has spent over 25 years developing and implementing scientific and clinical systems and evaluating their value.  Working with Dr. Clement McDonald, one of the pioneers of medical informatics, he has created an electronic patient record (called the Indiana Network for Patient Care) containing data from many sources including laboratories, pharmacies and hospitals in central Indiana.  The system currently connects nearly all acute care hospitals in central Indiana and includes inpatient and outpatient encounter data, laboratory results, immunization data and other selected data.  In order to create a sustainable financial model, he helped create the Indiana Health Information Exchange, a not-for-profit corporation.  Over the last five years, he has played a significant regional and national leadership role in advancing the policy, standards, financing and implementation of health information exchange.

Dr. Overhage is also an expert in clinical decision support including inpatient and outpatient computerized physician order entry and the underlying knowledge bases to support them.

Data Analysis

William M. Tierney, MD, is Director of the Regenstrief Center for Healthcare Improvement and Research (RCHIR) and Senior Research Scientist, Regenstrief Institute, Inc.; Chancellor's Professor in the Department of Medicine of the Indiana University School of Medicine; Director of Research for the Indiana University Kenya Program; and Indiana University Site Director for the National Health Information Technology Resource Center, AHRQ Resource Center for Practice-Based Research Networks.

Dr. Tierney is an internationally recognized expert in medical informatics and health services research, known for implementing and assessing electronic medical record systems to enhance quality of care. He led the team that was first to demonstrate that computerization of hospital orders can substantially reduce cost and medical errors.  The technology he evaluated now supports care for large patient populations in Indiana and sub-Saharan Africa.

In addition to informatics-based health services research, he has also performed dozens of epidemiologic studies utilizing the clinical data stored in the clinical data repositories created by the Regenstrief Institute and Indiana University's collaborative care program in east Africa.

Marc B. Rosenman, MD, Research Scientist, Regenstrief Institute, Inc.; Assistant Professor of Pediatrics, Children's Health Services Research, Indiana University School of Medicine, Director, Health Data and Epidemiology Section, Regenstrief Institute, and faculty supervisor for the Regenstrief Institute's data management group.

Dr. Rosenman's research focuses on clinical epidemiology, electronic medical records systems, and health information from multiple sources.

Education and Training

Kurt Kroenke, MD, Research Scientist, Regenstrief Institute, Inc.; Professor of Medicine, Indiana University School of Medicine.

Dr. Kroenke focuses his clinical research on the optimal evaluation and management of common symptoms such as pain, fatigue, dizziness, and other physical complaints. He also conducts research on depression, anxiety and other mental disorders in primary care. His methodologic expertise includes clinical trials, questionnaire development, clinical epidemiology, and health services research. He is the Director of Fellowship Programs for the Institute, and the Director of the Indiana University Clinical Investigator Training Enhancement (CITE) Program which provides a campus-wide Masters of Science in Clinical Research degree for fellows and junior faculty from numerous disciplines.

Center for Aging Research

Christopher M. Callahan, MD, Associate Director and Research Scientist, Regenstrief Institute, Inc.; Cornelius and Yvonne Pettinga Professor in Aging Research, Professor of Medicine, Indiana University School of Medicine; Director, Indiana University Center for Aging Research.

Dr. Callahan’s research seeks to improve the outcomes of care for older adults with late life depression and dementia. His work explores innovative models of care that support the generalist physician in their day-to-day provision of health care for older adults. These new models of care focus on collaboration between health care providers, patients, and family as well as across the continuum of care with an emphasis on the application of information technology.