About the Lab

Researchers in Regenstrief’s Drug Safety Informatics Lab leverage a robust repository of patient data, sophisticated clinical information systems, and expertise in pharmacoepidemiology, data mining, and natural language processing to improve the identification and communication of drug safety issues.  Regenstrief’s unique end-to-end role in the health care environment allows DSI researchers to not only conduct pharmacovigilance studies using observational data, but to influence the collection of key information at the point-of-care to improve these studies.

Ongoing research includes analysis of patterns in adverse event labeling, delivery of customized drug safety information based on patient characteristics, identifying novel drug interactions through literature mining and clinical validation, testing of novel statistical methodologies for pharmacovigilance, design of context-aware drug interaction alerting systems, and applications of information visualization in drug safety.

Researchers

Jon Duke, MD, MS  Director

Siu Hui, PhD

Lang Li, PhD

Xiaochun Li, PhD

Mick Murray, PharmD, MPH

Marc Rosenman, MD

Linas Simonatis, MD

Wanzhu Tu, PhD

Contact Us 

The DSI Lab collaborates actively with other academic centers as well as government and industry.  For inquiries regarding custom projects or supporting DSI activities, contact Dr. Jon Duke.