INDIANAPOLIS, US and LONDON, UK – Regenstrief Institute and SNOMED International have released LOINC® Ontology 2.82, the latest update to The LOINC Ontology: A LOINC and SNOMED CT Interoperability Solution, further advancing their collaboration to improve the exchange and use health data worldwide.
This new version builds on the enhancements introduced in LOINC Ontology 2.0 and extends coverage in laboratory domains, including coagulation and antibiotic susceptibility testing. These updates enhance LOINC Ontology’s ability to represent laboratory test semantics in a standards-aligned, computable framework that supports data exchange, analytics and clinical decision-making.
“These updates strengthen how observable health data is structured and shared globally,” said Marjorie Rallins, executive director of Health Data Standards at Regenstrief Institute. “By improving the structure of LOINC and its alignment with SNOMED International, we’re making health data more consistent, computable, and useful for care and research worldwide.”
Enhancements in version 2.82 focus on improving the clarity, consistency and computability of laboratory concepts. Updates include separating method or technique details from the LOINC Component field into a dedicated Method attribute, enabling more precise modeling and post-coordination. The release also refines how antibiotic susceptibility testing is represented by shifting explicit concentration values into the Method field, aligning with how laboratory procedures define antibiotic challenge conditions.
Additional improvements address consistency and quality across laboratory terminology, including resolving duplication, refining naming conventions and strengthening distinctions between substances and substance classes. These changes ensure key analytes are more accurately represented within Component attributes, supporting more reliable interpretation and reuse of laboratory data.
The LOINC Ontology version name 2.82 reflects alignment with the LOINC release cycle, with version 2.82 corresponding directly to LOINC 2.82, which was released February 24, 2026. This approach provides a clear connection between LOINC Ontology updates and their source content, helping implementers track changes and coordinate updates across tools, guides and implementation workflows. This versioning strategy supports predictable biannual updates that parallel the established LOINC update cadence.
Ongoing collaborative development
The collaboration between Regenstrief and SNOMED International continues to expand the LOINC Ontology’s coverage, usability and value for global implementers. Following the introduction of orderable grouper structures and expanded content in version 2.0, this release further strengthens the representation of critical laboratory data needed for both clinical and secondary uses of health data.
For more information and to browse and download the LOINC Ontology, visit https://loincsnomed.org.
About LOINC®
LOINC® was created in 1994 at Regenstrief Institute to facilitate interoperability in healthcare. There was a growing trend to send clinical data electronically between healthcare entities, a practice that has now become ubiquitous. Today, it contains more than 108,000 concepts for everything from an albumin level to a zygomatic arch X-ray report. For each concept, LOINC contains many other rich details, such as synonyms, units of measure and carefully crafted descriptions.
About SNOMED International
SNOMED International is a global, not-for-profit organization that develops and maintains SNOMED CT, the world’s most comprehensive clinical terminology, enabling the consistent, accurate exchange of health information to support better patient care, health outcomes, and system performance worldwide. Learn more at www.snomed.org.
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