Influence
October 7, 2020

Evaluating the link between medications and dementia: Regenstrief researcher provides consultation

Regenstrief Institute research scientist Noll Campbell, PharmD, M.S., recently contributed to a study that made national headlines and provided more evidence that anticholinergic medications are linked to cognitive decline.

The results from the study, led by researchers at the University of California San Diego School of Medicine, were published in Neurology. The authors concluded that anticholinergics are associated with an increased risk of cognitive decline regardless of the presence of genetic or biomarker risk factors for Alzheimer’s disease.

Dr. Campbell consulted on the study, providing perspective on the data based on similar studies he has been involved with at Regenstrief and Indiana University School of Medicine.  He is listed as an author on the paper.

The past research conducted by Dr. Campbell and his colleagues also provides evidence establishing a link between the common type of medication and cognitive decline. He is now leading a clinical trial to determine if deprescribing anticholinergics improves cognition, which could in turn delay or prevent dementia.

In addition to his role as a research scientist at Regenstrief Institute, Dr. Campbell is an assistant professor of pharmacy practice at the Purdue University College of Pharmacy.

Related News

Fairbanks, Lilly, Regenstrief and Indiana employers collaborate to study obesity medications’ impact

Fairbanks, Lilly, Regenstrief and Indiana employers collaborate to study obesity medications’ impact

INDIANAPOLIS — Researchers from the Fairbanks School of Public Health at Indiana University Indianapolis have launched a first-of-its-kind study

Music for the brain: Study tests the effect of slow-tempo relaxing music to address delirium in critically ill older adults

Music for the brain: Study tests the effect of slow-tempo relaxing music to address delirium in critically ill older adults

Findings support longer-duration or targeted approaches A multi-center randomized controlled trial with critically ill adults aged 50 years and

Regenstrief experts lead, to present at 2nd biennial HEALeR symposium to explore ethics in learning health systems

The HEALeR Consortium will host its second biennial Symposium on November 6, 2025, at the NCAA Conference Center, 700

Regenstrief scientist elected to American College of Medical Informatics

Kun Huang, PhD, research scientist at the Clem McDonald Center for Biomedical Informatics at the Regenstrief Institute, has been