Building access to the Regenstrief Institute is currently restricted. More on our coronavirus precautions.
See our coronavirus precautions.

Indiana University Center for Aging Research at Regenstrief Institute Associate Director Babar Khan, M.D., M.S., has been treating patients in the intensive care unit (ICU) throughout the COVID-19 pandemic.  

Dr. Khan said many patients continue to suffer from mental, physical and emotional impairments after being released from the ICU, and those problems can persist for months. He shared his experience with national media, including Kaiser Health News.  

He reported that older adults in the ICU with COVID-19 are suffering from delirium 70 to 80 percent of the time. Seniors are especially susceptible to delirium, which is a sudden change in brain function, when they are hospitalized for serious illnesses. Delirium in older adults is associated with an increased risk of losing independence, developing dementia and death 

Dr. Khan said given the extent of delirium and mounting evidence of neurological damage from COVID-19, he expects to see an increase in the prevalence of ICU-acquired cognitive impairment.  

Even younger patients may face a long recovery after time spent in the ICU.  

Dr. Khan helped develop the critical care recovery center model, dedicated to long-term recovery from intensive care. He works with patients at Eskenazi Health after they have been discharged from the ICU to help them recover from physical, emotional and mental symptoms that continue to linger.  

Dr. Khan and his colleagues are also conducting research to prevent, diagnose and treat delirium.  

Read about cognitive impairment in COVID-19 survivors

Listen to Dr. Khan discuss ICU recovery in an episode of The Problem podcast from Regenstrief.  

In addition to his role at Regenstrief, Dr. Khan also serves as an associate professor of medicine at Indiana University School of Medicine and a physician at Eskenazi Health.  

Related Influence

Jul 07, 2021 • Influence
Algorithm developed by Regenstrief/Merck collaboration hailed as promising research tool
A natural language processing (NLP) algorithm to identify patients with chronic cough, created and validated by Regenstrief Institute, Indiana University and Merck & Co. research scientists, is being recognized for its ingenuity and its potential.   The paper describing the algorithm’s development, Identifying and Characterizing a Chronic Cough Cohort Through Electronic Health Records, was published in the June 2021 edition of Chest Journal, along with an editorial written…
Continue Reading >
Jun 22, 2021 • Influence
Regenstrief experts share cancer-related research as part of IU Simon Cancer Center Series
Two Regenstrief research scientists who focus on cancer research are sharing their knowledge in the Indiana University Melvin and Bren Simon Comprehensive Cancer Center’s monthly series called “Simon Says.”  The monthly virtual series was created to better connect cancer experts with the community, giving people the opportunity to hear about the latest research and ask questions.   [caption…
Continue Reading >