Published in Journal of the National Comprehensive Cancer Network. Here is a link to the article.
Regenstrief Institute author: , MD, MS
The NCCN Guidelines for Colorectal Cancer (CRC) Screening provide evidence-based recommendations for screening individuals at average or increased risk of sporadic CRC, excluding those with known genetic syndromes. These guidelines assist clinicians in selecting appropriate screening modalities and schedules.
Recent updates emphasize both primary and secondary CRC prevention, with a notable focus on the age to begin screening. A key change includes new guidance for individuals with a personal history of childhood, adolescent, or young adult (CAYA) cancer, who are at elevated risk due to prior treatments like chemotherapy or radiation. The updated recommendations suggest tailored screening initiation ages for this group to improve early detection and outcomes.
Overall, the guidelines promote a more personalized approach to CRC screening, supporting risk-based decision-making to enhance prevention and reduce CRC-related morbidity and mortality.
Authors
Affiliations
1Vanderbilt-Ingram Cancer Center.
2Yale Cancer Center/Smilow Cancer Hospital.
3Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
4University of Michigan Rogel Cancer Center.
5Stanford Cancer Institute.
6Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
7Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
8Moffitt Cancer Center.
9UT Southwestern Simmons Comprehensive Cancer Center.
10Johns Hopkins Kimmel Cancer Center.
11Roswell Park Comprehensive Cancer Center.
12Mayo Clinic Comprehensive Cancer Center.
13Fox Chase Cancer Center.
14Huntsman Cancer Institute at the University of Utah.
15Fred Hutchinson Cancer Center.
16Abramson Cancer Center at the University of Pennsylvania.
17City of Hope National Medical Center.
18Fred & Pamela Buffett Cancer Center.
19Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
20Memorial Sloan Kettering Cancer Center.
21UC Davis Comprehensive Cancer Center.
22UCLA Jonsson Comprehensive Cancer Center.
23Dana-Farber Cancer Institute.
24The UChicago Medicine Comprehensive Cancer Center.
25University of Colorado Cancer Center.
26O’Neal Comprehensive Cancer Center at UAB.
27Independent Patient Advocate.
28The University of Texas MD Anderson Cancer Center.
29The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute.
30UCSF Helen Diller Family Comprehensive Cancer Center.
31UC San Diego Moores Cancer Center.
32University of Wisconsin Carbone Cancer Center.
33The University of Tennessee Health Science Center.
34National Comprehensive Cancer Network.
The Latest
