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Regenstrief Institute, Inc.

Better care. Better health.

The Regenstrief Institute is an internationally respected informatics and healthcare research organization, recognized for its role in improving quality of care, increasing efficiency of healthcare delivery, preventing medical errors and enhancing patient safety. Established by philanthropist Sam Regenstrief on the Indiana University - Purdue University Indianapolis campus in 1969, the Institute is a 501(c)(3) organization closely associated with the Indiana University School of Medicine and the Health and Hospital Corporation of Marion County, Indiana’s Wishard-Eskenazi Health.

Institute investigators and affiliated scientists form a talented cadre of researchers. This includes Interim President and CEO Christopher Callahan, MD, who is also the Director of the Indiana University Center for Aging Research, Shaun Grannis, MD, MS, FAAFP, Interim Director for the Regenstrief Center for Biomedical Informatics, and Michael Weiner, MD, MPH, Director of the Regenstrief Center for Health Services Research and the IU Center for Health Services and Outcomes Research.

Eskenazi Health, one of the five largest public health systems in the United States, serves as "laboratory" for a large number of Regenstrief studies. Regenstrief also partners with IU Health and the Richard L. Roudebush VAMC.

The Institute receives core support from the Regenstrief Foundation. Grants and contracts from the National Institutes of Health, the Agency for Healthcare Research and Quality, the Centers for Disease Control and Prevention, other governmental agencies, national philanthropies, Indianapolis healthcare institutions, and additional sources fund Institute activities.

Institute research findings have been published in the New England Journal of Medicine, the Journal of the American Medical Association, Journal of General Internal Medicine, Archives of Internal Medicine, Journal of the American Medical Informatics Association, Journal of the American Geriatrics Society, Pediatrics, and numerous other prominent peer-reviewed journals. 

Institute research has been translated into local, regional and national practice. 




Creating pathways for better health