Influence
May 1, 2025

Medicaid Unwinding and Changes in Buprenorphine Dispensing

Kosali Simon, PhD

Published in JAMA Network Open. Here is a link to the article.

Regenstrief Institute authors: Kosali Simon, PhD, M.A.

A new national study has found that the Medicaid unwinding process following the end of the continuous enrollment provision was associated with significant disruptions in access to buprenorphine therapy among adult Medicaid beneficiaries. Utilizing data from over 750,000 person-years across 46 states and the District of Columbia, the analysis compared states with the highest versus lowest drops in Medicaid enrollment between 2023 and the baseline.

The findings indicate that patients in states with the largest disenrollment saw a reduction in the number of days with active buprenorphine prescriptions and were more likely to have no active prescription at all. These patients were also more likely to shift to private insurance or pay out-of-pocket for treatment, reflecting increased financial barriers to care. Notably, patients with less consistent buprenorphine use prior to disenrollment experienced the sharpest declines in therapy continuation.

The data suggest that Medicaid disenrollment may have limited access to this critical medication for opioid use disorder, potentially worsening outcomes amid the ongoing opioid epidemic. The study also highlights that patients previously using only branded buprenorphine products were disproportionately affected, likely due to higher costs.

While limitations include the inability to directly identify individuals disenrolled from Medicaid, the consistent trends across multiple analyses point to a clear association between coverage loss and therapy disruption. The results underscore the need for policy interventions to maintain continuity of care during insurance transitions, particularly for populations at risk of opioid-related harm.

Authors:

Joanne Constantin1, Genevieve M Kenney2, Kosali Simon3, Kao-Ping Chua1,4

Affiliations

1Susan B. Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor.

2Health Policy Center, Urban Institute, Washington, DC.

3Paul H. O’Neill School of Public and Environmental Affairs, Indiana University, Bloomington.

4Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor.

Partners

Related News

(From left to right) Dr. Brian Dixon, Dr. Sanji De Sylva and Isaac Vetter. Photo credit: Svetlana Efimova

Regenstrief experts advance global dialogue on digital health and interoperability at forum in Dubai

Regenstrief informaticians joined global leaders who shared their expertise at the 8th ZIMAM Digital Health Forum November 5-6, in

Regenstrief researchers join national stage to advance aging and gerontology research

Regenstrief Institute research scientists joined leading experts from across the nation at the Gerontological Society of America (GSA) 2025

illustration of the combination of interventions used in the D3 pragmatic clinical trial

Zero-cost, AI-driven digital detection identifies Alzheimer’s and related dementias without additional clinician time

Few primary care practices are designed for the timely detection of Alzheimer’s disease and related dementias. The limited time