May 19, 2022

Patient safety and quality of care: Regenstrief study explores medical record linkage with goal of improving match accuracy

Shaun Grannis, MD, MS

Accurate linking of medical records from different sources, known as patient matching, plays a critical role in patient safety and quality of medical care, but has proven difficult to accomplish. A new study from the Regenstrief Institute is one of the first to evaluate commercially available matching methodologies in comparison to real-world gold standard data with the goal of identifying evidence-based opportunities for improving match accuracy for record linkage.

“Healthcare providers need securely shared access to all available data on an individual to make the best care decisions, yet patient data remains fragmented,” said Regenstrief Institute Vice President for Data and Analytics and Indiana University School of Medicine Professor Shaun Grannis, M.D., M.S., who led the study. “Name variations, typographic or recording errors, missing information, as well as name, address and phone number changes and other issues make record linkage daunting.”

To ensure effective data sharing, electronic health records (EHRs) — both within one office or hospital system and among different healthcare organizations — must accurately refer to a single, specific individual. Is the Robert Smith seen at one medical office the same person as the Robert Smith, Rob Smith or Bob Smith seeking care at a different facility? Are his health records comprehensively linked? To which Maria Garcia do various lab test results belong? Which Mike Miller was the one hospitalized for COVID-19 who requires long-term post-pandemic care?

Noting that there is no evidence-based “best” patient matching approach, the study authors compared the algorithms of probabilistic matching and the increasingly popular referential method of record linking to the gold standard of manually reviewed information from the Indiana Network for Patient Care (INPC), one of the nation’s largest health information exchanges with 47 million patient registrations. The researchers found that referential patient matching, which employs data from commercially available, non-healthcare sources, including credit header data and federal, state and local government person records, demonstrated greater sensitivity and accuracy than the more traditional probabilistic approach.

The authors noted, “As the United States continues to advance a national identity strategy for healthcare, a more consistent and broadly deployed approach to objectively evaluating matching algorithms is necessary to provide transparency and support healthcare organizations in adopting evidence-based best practice guidelines for patient matching algorithms. Consequently, health IT policymakers, including the ONC [Office of the National Coordinator], should explore strategies for expanding the evidence base for real-world matching system performance and encourage development of more consistent and transparent approaches to assessing and disseminating matching system performance.”

Evaluation of Real-World Referential and Probabilistic Patient Matching to Advance Patient Identification Strategy” is published online ahead of print in JAMIA (Journal of the American Medical Informatics Association).

Co-authors of the study, in addition to Dr. Grannis, are Jennifer L. Williams, MPH, Regenstrief Institute; Suranga Kasturi, PhD, Regenstrief Institute and IU School of Medicine; Molly Murray, MPA, Pew Charitable Trust; and Huiping Xu, PhD, IU Richard M. Fairbanks School of Public Health.

The study was funded by the California HealthCare Foundation.

About Shaun Grannis, M.D., M.S.
In addition to his role as vice president for data and analytics at Regenstrief Institute, Shaun Grannis, M.D., M.S., is the Regenstrief Professor of Medical Informatics and a professor of family medicine at Indiana University School of Medicine.

About Regenstrief Institute
Founded in 1969 in Indianapolis, the Regenstrief Institute is a local, national and global leader dedicated to a world where better information empowers people to end disease and realize true health. A key research partner to Indiana University, Regenstrief and its research scientists are responsible for a growing number of major healthcare innovations and studies. Examples range from the development of global health information technology standards that enable the use and interoperability of electronic health records to improving patient-physician communications, to creating models of care that inform practice and improve the lives of patients around the globe.

Sam Regenstrief, a nationally successful entrepreneur from Connersville, Indiana, founded the institute with the goal of making healthcare more efficient and accessible for everyone. His vision continues to guide the institute’s research mission.

About IU School of Medicine
IU School of Medicine is the largest medical school in the U.S. and is annually ranked among the top medical schools in the nation by U.S. News & World Report. The school offers high-quality medical education, access to leading medical research and rich campus life in nine Indiana cities, including rural and urban locations consistently recognized for livability.

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