Influence
January 14, 2025

Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement

Sarah Wiehe, MD

Published in JAMA. Here is a link to the article.

Regenstrief Institute authors: Sarah Wiehe, MD, MPH

The U.S. Preventive Services Task Force (USPSTF) evaluated the benefits and harms of osteoporosis screening to prevent fractures in adults aged 40 or older without a known diagnosis of osteoporosis or prior fragility fractures. Osteoporotic fractures can lead to psychological distress, additional fractures, loss of independence, reduced daily functioning, and death. Based on a systematic review, the USPSTF concludes with moderate certainty that screening provides a moderate net benefit for women aged 65 and older, and for postmenopausal women under 65 who are at increased risk for fractures based on clinical risk assessment. The USPSTF recommends screening these groups (B recommendation). However, the USPSTF finds the current evidence insufficient to determine the balance of benefits and harms of screening in men.

Authors:

US Preventive Services Task ForceWanda K Nicholson 1Michael Silverstein 2John B Wong 3David Chelmow 4Tumaini Rucker Coker 5Esa M Davis 6Carlos Roberto Jaén 7Marie Krousel-Wood 8Sei Lee 9Li Li 10Carol M Mangione 11Gbenga Ogedegbe 12Goutham Rao 13John M Ruiz 14James Stevermer 15Joel Tsevat 7Sandra Millon Underwood 16Sarah Wiehe 17

Affiliations

1George Washington University, Washington, DC.

2Brown University, Providence, Rhode Island.

3Tufts University School of Medicine, Boston, Massachusetts.

4Virginia Commonwealth University, Richmond.

5University of Washington, Seattle.

6University of Maryland School of Medicine, Baltimore.

7University of Texas Health Science Center, San Antonio.

8Tulane University, New Orleans, Louisiana.

9University of California, San Francisco.

10University of Virginia, Charlottesville.

11University of California, Los Angeles.

12New York University, New York, New York.

13Case Western Reserve University, Cleveland, Ohio.

14University of Arizona, Tucson.

15University of Missouri, Columbia.

16University of Wisconsin, Milwaukee.

17Indiana University, Bloomington.

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