As the world deals with the COVID-19 pandemic, millions of Americans continue to battle substance use disorder. September is National Recovery Month, and Indiana University is celebrating the faculty who are leading the effort to help people recover. Debra Litzelman, M.D., M.A., associate director of the Regenstrief Institute Center for Health Services Research, is leading […]

Regenstrief, IU team developing technologies to analyze social determinants of health COVID-19 is disproportionately affecting minorities, and experts believe many of the disparities are driven by underlying social risk factors, such as socioeconomic status or access to healthcare. A team of Regenstrief Institute and Indiana University Richard M. Fairbanks School of Public Health at IUPUI […]

Program will support researchers interested in creating startups Regenstrief Institute has selected four research scientists for its first class of Regenstrief Venture Fellows. The new program will support researchers in exploring the commercial potential of their ideas and learning how to launch a startup. “The new fellowship program is an exciting opportunity for Regenstrief to […]

Research will examine collection and formatting of patient demographic data Regenstrief Institute is working with the Pew Charitable Trusts and the Center for Health Information Partnerships at Northwestern University to shed light on the collection and formatting of demographic data used to link patient records with the goal of making the process easier and more […]

Regenstrief research scientist and IUPUI professor NiCole Keith, PhD, has become the 64th president of the American College of Sports Medicine (ACSM), which is headquartered in Indianapolis. She is the first person of color to hold this position. Renowned for her work in community activation and physical fitness, Dr. Keith has been instrumental in Indianapolis health […]

Regenstrief Institute research scientist Michael “Mick” Murray, PharmD, MPH, is retiring after decades of groundbreaking work. He has been with the institute for 34 years while pioneering in the field of pharmacoepidemiology. He is the Purdue College of Pharmacy Distinguished Professor of Pharmacy Practice and Endowed Chair of Medication Safety. Dr. Murray began work at […]

Regenstrief Institute research scientist Sarah E. Wiehe, M.D., MPH, will co-lead the Indiana Clinical and Translational Sciences Institute (CTSI) along with Sharon M. Moe, M.D. Indiana CTSI is focused on improving health in Indiana through a research partnership among the state’s leading research universities of Indiana University (IU), Purdue University and the University of Notre […]

Regenstrief Vice President calls for action in JAMA Health Forum As protests for racial justice take place across the country, Regenstrief vice president for faculty development and nationally recognized public health expert, Aaron Carroll, M.D., details the systemic racism present in healthcare and urges immediate action to address the inequities that are killing Black Americans. […]

VIEW RECORDINGS OF THE CONFERENCE More than 500 people from 16 countries engaged in a dynamic discussion on artificial intelligence (AI) in healthcare hosted by Regenstrief Institute and Indiana Clinical and Translational Sciences Institute (CTSI). The three-day virtual event, Artificial Intelligence: Applying Research and Engineering Solutions for Emergent Needs in Healthcare, featured international thought leaders […]

VIEW RECORDINGS OF THE CONFERENCE Starting today, June 1, at 11 a.m., more than 430 people from 16 countries are participating in a virtual conference focused on applying artificial intelligence (AI) for healthcare hosted by Regenstrief Institute and Indiana Clinical and Translational Sciences Institute (CTSI). Over the course of three days, “Artificial Intelligence: Applying Research […]

Regenstrief Institute and Indiana University School of Medicine research scientist Kun Huang, PhD, is leading a team as part of the Indiana University Alzheimer’s disease drug discovery center. Dr. Huang is the director of the bioinformatics and computational biology core of the center, which is funded by the National Institute on Aging (NIA), part of […]

Hospital systems across the country are forming new partnerships to share data in light of the COVID-19 pandemic. Regenstrief Institute and its role in Indiana’s statewide data-sharing effort were featured in Becker’s Hospital Review. The institute and its partners created a dashboard that tracks hospitalizations related to the novel coronavirus across the state. In an […]

VIEW RECORDINGS OF THE CONFERENCE Regenstrief Institute and the Indiana Clinical and Translational Sciences Institute (CTSI) are hosting international thought leaders in artificial intelligence (AI) applications for an engaging virtual conference. “Artificial Intelligence: Applying Research and Engineering Solutions for Emergent Needs in Healthcare” will feature insights from academic, industry, government and clinical partners on June […]

IU/Indiana State Department of Health release initial findings Preliminary results from a scientific study aimed at measuring the spread of the novel coronavirus in Indiana show a general population prevalence of about 2.8 percent of the state’s population. “What we knew through conventional detection methods — testing symptomatic people and those at high-risk for COVID-19 […]

Republished from News at IU In response to the COVID-19 pandemic, the Indiana State Department of Health has formed a partnership with Probari Inc., a Central Indiana startup committed to improving the overall health care experience of residents at nursing homes and long-term care facilities. The agreement was reached to provide training and support to more […]

Videos from conference sponsored by Regenstrief, Harvard and Stanford now available online Regenstrief Institute, Harvard University and Stanford School of Medicine hosted an online conference exploring the opportunities for leveraging artificial intelligence to improve the lives of people with disabilities and dependencies, and the entire discussion is now available for free online. AI has potential […]

The Indiana State Department of Health (ISDH) is collaborating with the Indiana University Richard M. Fairbanks School of Public Health at IUPUI to conduct a scientific study to measure current and past extent of COVID-19 infection throughout the state. Unlike most current testing nationwide, which has focused on individuals who are actively ill and healthcare […]

New data sharing effort could be used to enhance disease tracking The Indiana Network for Population Health (INPH) has been launched by the Regenstrief Institute and collaborators, including the State of Indiana, Indiana University and the Indiana Health Information Exchange, to provide the secure exchange of comprehensive data — especially information on social determinants of […]

Regenstrief, IU Kelley School of Business, and SoPE hosting webinar on collaborative care strategies The COVID-19 pandemic has changed communication and workflow for nearly everyone, including healthcare workers. Regenstrief Institute, the Indiana University Kelley Business of Medicine Program and the Society of Physician Entrepreneurs (SoPE) Indiana Chapter are hosting a webinar to offer strategies and […]

LOINC®, an international health data standard maintained at Regenstrief Institute, is hosting a special public meeting to address the coronavirus pandemic. More than 600 people from around the world are signed up to attend the virtual event on March 26 related to LOINC coding for SARS-CoV-2/COVID-19. In response to the coronavirus pandemic, LOINC has created […]

Regenstrief, Harvard University and Stanford School of Medicine co-sponsoring conference Artificial intelligence (AI) can improve the lives of people with disabilities and dependencies, but it can also perpetuate discriminatory biases and cause unintended harm. Regenstrief Institute, Harvard University and Stanford University School of Medicine are co-sponsoring a conference to explore the best practices to harness […]

Regenstrief Institute research scientist Michael Weiner, M.D., MPH, led a Scottsdale Institute webinar and presented his recent research findings related to hypoglycemia. Dr. Weiner explained the statistical modeling that identified the magnitude of risk factors for hypoglycemia. He also discussed a pilot study using continuous glucometers and other wearable devices designed to make better predictions […]

Regenstrief, IU Fairbanks researcher to present use case at HIMSS20 Incorporating social determinants of health into a patient’s health records is an area of significant interest for health systems, but many are finding the integration to be challenging. Regenstrief Institute and Indiana University Richard M. Fairbanks School of Public Health at IUPUI researcher Brian Dixon, […]

Admission to the hospital and being seen by a neurologist are factors associated with better quality care for people with a transient ischemic attack (TIA), also known as mini-stroke, according to new research led by scientists from the U.S. Department of Veterans Affairs, Regenstrief Institute, Purdue University, and Indiana University. The study looked at patients […]

Artificial intelligence offers exciting opportunities to improve care, but there are many considerations as the field moves forward. Stakeholders can now take an online course on Regenstrief Institute’s website that gives insight into the current and future state of AI as well as best practices for development, implementation and maintenance moving forward. The 11-video course […]

The world is focused on the outbreak of respiratory illness caused by a novel coronavirus. The World Health Organization (WHO) has named the syndrome caused by this coronavirus “COVID-19”, and the International Committee on Taxonomy of Viruses (ICTV) has named the virus “Severe acute respiratory syndrome coronavirus 2” or SARS-CoV-2. As part of the global […]

Several Regenstrief Institute and Indiana University School of Medicine research scientists are part of a major study looking at how youth who have been arrested experience substance use disorders and the steps that can be taken to help them receive treatment. The researchers will implement a learning health system as well as utilize data available […]

Dr. Paul Dexter responds to study from Yale School of Medicine In a recent study published in the journal Mayo Clinic Proceedings, physicians gave electronic health records systems very low ratings for user experience. Regenstrief Institute and Indiana University School of Medicine researcher and EHR expert Paul Dexter, M.D., said he found it disappointing that […]

Regenstrief Institute welcomed informatics expert James Cimino, M.D., for its January SAM (Scientists Advancing Medicine) Talk, presented in collaboration with the Indiana University School of Informatics and Computing at IUPUI Colloquia Series. Dr. Cimino has been a clinician, an informaticist, a systems architect and an educator for more than 30 years. His specialty is clinical […]

Clinician decision support app spreading across an entire state Doctors at Indiana University Health hospitals now have faster, easier access to information about the patients they are treating in the emergency department. The app, created in a partnership among Regenstrief Institute, Indiana Health Information Exchange (IHIE), IU Health and Indiana University School of Medicine, provides clinicians […]

Frances (Fran) Valentine has been named the director of operations for the Indiana University (IU) Center for Aging Research at Regenstrief Institute. Valentine is an experienced administrator with skills in federal grants administration, budget management and reporting. Most recently, Valentine was the senior director of research analysis and engagement at the Indiana Department of Workforce […]

Johanne Eliacin, PhD, a Regenstrief Institute and U.S. Department of Veterans Affairs research scientist, received a Congressional Black Caucus Veterans Braintrust Award for her research to reduce healthcare disparities for minority veterans. Dr. Eliacin presented her work on improving minority veterans’ experience with VA mental health services to the Congressional Black Caucus Veterans Braintrust (CBCVB) […]

Regenstrief research scientist Debra K. Litzelman, M.D., M.A., joined U.S. Surgeon General Jerome Adams, M.D., and other Indiana University faculty members to discuss ways that global health work can improve health in America. Dr. Litzelman, also a professor of medicine at Indiana University School of Medicine, elaborated on her work with the WeCare program, which […]

Shaun Grannis, M.D., M.S., an internationally recognized expert in informatics, data analytics, and biosurveillance, has been named the Regenstrief Institute’s first vice president for data and analytics. Dr. Grannis most recently served as the director of the Regenstrief Institute’s Clem McDonald Center for Biomedical Informatics. In this new role, Dr. Grannis will serve as part […]

Jennifer Sullivan, M.D., MPH, secretary of the Indiana Family and Social Services Administration (FSSA), has joined Regenstrief Institute’s Board of Directors. Regenstrief’s board provides strategic guidance, oversight and management for the internationally respected medical research organization in support of its mission to improve local, national and global delivery and outcomes of healthcare through research and […]

Patients with chronic diseases such as breast cancer or colorectal cancer often experience fatigue, pain, depression and other symptoms which can lead to distress and functional impairment if left untreated. With the ultimate goal of helping clinicians manage and treat symptoms that negatively affect health and quality of life, researchers from the Regenstrief Institute and […]

Two of Regenstrief Institute’s leaders are sharing their expertise in artificial intelligence and data infrastructure at a workshop hosted by Brazil’s National Institute of Science and Technology in Scientific Assisted Medicine in Sao Paulo, Brazil. Regenstrief’s Vice President for Research, Eneida Mendonca, M.D., PhD, will speak Thursday, Oct. 17 and Friday, Oct. 18, about the […]

Peter Embí, M.D., M.S., president and chief executive officer of Regenstrief Institute, has been named to the National Advisory Council for the Agency for Healthcare Research and Quality (AHRQ). The appointment gives Dr. Embí a unique opportunity to help guide research priorities on a national level. AHRQ is an agency within the U.S. Department of […]

Data is transforming healthcare delivery, and Regenstrief President and Chief Executive Officer Peter Embí, M.D., is providing insight into utilizing that data to healthcare leaders from across the country. Dr. Embí led a discussion panel in the Health Data Leadership Institute in Washington, D.C.  He is an internationally recognized researcher, educator and leader in the […]

$3.5 million grant awarded to study effectiveness of POLST form facilitation A team led by Regenstrief researcher Alexia Torke, M.D., is exploring if guidance in filling out medical treatment options on the POLST form makes a measurable difference in a person’s care preferences being respected. The advance care planning assistance will be provided by trained […]

Regenstrief Institute Senior Research Manager Laura Holtz, M.S., will be a plenary presenter at the annual conference of the Society of Clinical Research Associates (SOCRA). Holtz is a national leader in research and is dedicated to educating other research professionals. Holtz will speak to conference attendees about strategies to include vulnerable subjects with cognitive impairment […]

Malaz Boustani, M.D., MPH, detailed his career journey and his work in the areas of brain care research and implementation science on the podcast Outcomes Rocket. Dr. Boustani is a research scientist at Regenstrief Institute in Indianapolis, the founding director of the Center for Health Innovation and Implementation Science and associate director of the Indiana […]

The Regenstrief Institute will host another meeting of the Indiana Chapter of the Society of Physician Entrepreneurs (SoPE) on August 15, 2019. “SoPE presents an opportunity for Regenstrief to connect and innovate with a community of leaders interested in converting evidence into good business practices,” said Regenstrief Manager of Business Development Chris Frederick. “By bringing […]

Susan Hickman, Ph.D., has been selected to lead the Indiana University Center for Aging Research at the Regenstrief Institute. She will be the second director in the center’s history. Dr. Hickman is a clinical geropsychologist focused on optimizing the quality of life for older adults through improved decision-making and communication about treatment preferences. Much of […]

Regenstrief research scientist Noll Campbell, PharmD, M.S., spoke about a common class of drugs and how it affects the brain on an Indianapolis radio show. Dr. Campbell was a guest on Caregiver Crossing, which airs every Saturday on 93.1 WIBC. Dr. Campbell addressed the topic of anticholinergics and their potential link to Alzheimer’s and dementia. […]

Regenstrief Institute’s Babar Khan, M.D., M.S., a renowned delirium researcher and clinician, has been chosen to lead the American Delirium Society. Dr. Khan has completed extensive studies about preventing and treating delirium in the ICU, identifying biomarkers associated with delirium and improving outcomes for the people who suffer from it. Dr. Khan will be installed […]

A new tool seeks to predict the severity of patients’ postoperative delirium and help practitioners more effectively care for patients as they recover from surgery. Currently providers only have tools for predicting whether or not patients will develop delirium, not its severity. Regenstrief Institute fellow Heidi Lindroth, Ph.D., and Robert D. Sanders, M.D.’s team at […]

By Gregory Schmidt, MD & Theresa Cullen, MD, MS Healthcare in America is a pairing of extremes. When ranked, the United States has some of the very best and the very worst healthcare metrics. Cancer survival remains the highest of any country, yet maternal deaths and infant deaths rank the worst of all developed nations. […]

Regenstrief researcher receives $3.3 million NIA award for cause and effect study Regenstrief Institute research scientist Noll Campbell, PharmD, MS has received a five-year $3.3 million award from the National Institute on Aging (NIA) to conduct the first clinical trial designed to determine if stopping anticholinergic medications results in sustained improvements in cognition. Anticholinergic medications […]

NiCole Keith, PhD, FACSM, has been elected president of the American College of Sports Medicine. Her presidency will begin in June 2020. 

Regenstrief Institute has an impressive portfolio of research, ranging from invention to implementation. The myriad discoveries, analyses and validations led by our investigators continue to make significant impacts in a wide variety of healthcare environments, including hospitals, outpatient clinics, doctors’ offices, nursing facilities and even homes. I am continuously impressed and inspired by the breadth […]

SymTrak advances clinicians toward next generation of population health management. An easy to use, brief, inexpensive new tool developed and validated by researchers at the Regenstrief Institute and Indiana University will help healthcare providers track and potentially identify early onset of more complex, serious underlying issues that could otherwise go undetected. The tool tracks symptoms […]

Research coordinator plays crucial role in meta-analysis review that determined FIT tests are effective in screening for colon cancer.

Umberto Tachinardi, M.D., has been named as the director of clinical research informatics for Regenstrief Institute and Indiana Clinical and Translational Sciences Institute (CTSI). Dr. Tachinardi is also serving as the chief informatics officer for the Indiana University Grand Challenge Precision Health Initiative. At the Indiana University School of Medicine, he is a professor of […]

The Boston Globe featured an Eskenazi Health program led by Regenstrief Research Scientist Malaz Boustani, M.D.

Regenstrief Institute faculty members Shaun Grannis, M.D., M.S., and Josh Vest, PhD, traveled to Texas to share the latest research from Regenstrief and offer advice to medical leaders as they prepare to launch a regional health information exchange (HIE). Dr. Grannis and Dr. Vest gave a presentation at the Health Informatics Grand Rounds at the […]

The key? Changing public health reporting from passive to proactive

Daniel Bateman, M.D., says a number of studies show a higher rate of Alzheimer’s disease in African Americans. He told USA Today there are some hypotheses to explain this. “There are higher rates of diabetes, hypertension, high cholesterol, heart disease and diabetes in African Americans compared to whites. All of those are risk factors for […]

Nation’s health and biomedical informatics professionals announce 2019 initiative to build on these recommendations and better operationalize scientific discovery for patient care. Editor’s note: Peter Embi, MD, MS, FACP, FACMI, FAMIA, is the lead author on this paper. He is the president and chief executive officer of Regenstrief Institute, in addition to the board chairman of […]

A study examining the effect of a video educational intervention aimed at increasing HPV vaccinations among adolescents could help the Centers for Disease Control and Prevention meet its goal of getting more eligible adolescents vaccinated against certain cancers and diseases caused by the human papillomavirus (HPV). The research, performed by Regenstrief Institute, Indiana University School […]

Findings are the result of a year-long collaboration of Roche Diabetes Care GmbH, IBM, Eli Lilly and Company, the Regenstrief Institute and the Indiana Bioscience Research Institute. A leading scientific journal, Nature Medicine, has published a major study online on how real-world patient data can better predict diabetes-related kidney disease in patients with the chronic […]

WASHINGTON, D.C. — Regenstrief Center for Biomedical Informatics Director Shaun Grannis, M.D., took part in a Pew Charitable Trust panel to discuss how to better match patients with their correct electronic health record and improve patient care. Electronic health records allow care providers the ability to exchange individuals’ health data with their colleagues elsewhere. However, […]

The American College of Medical Informatics announced that Brian Dixon, PhD, of Regenstrief Institute and the Indiana University Richard M. Fairbanks School of Public Health will be one of 18 fellows inducted into its ranks on November 4 in San Francisco at ceremonies during the American Medical Informatics Association (AMIA) 2018 Annual Symposium.

Aaron E. Carroll, M.D., a nationally recognized research scientist, research team leader and a New York Times writer and book author, has been selected as Regenstrief Institute’s first-ever vice president for faculty development.

Regenstrief investigator JT Finnell, M.D., has been elected to the Board of Directors for the American College of Emergency Physicians (ACEP). Dr. Finnell was elected during the organization’s annual meeting, which is the largest gathering of emergency physicians in the country. The board is the policymaking body, responsible for ACEP’s management and control. Dr. Finnell’s […]

Regenstrief Institute investigator Josh Vest, PhD, is one of three finalists in the BioCrossroads Inject Tech Challenge. In addition to his work at Regenstrief, Vest is an associate professor and director for the Center for Health Policy at the Indiana University Richard M. Fairbanks School of Public Health. Vest is developing a platform to access […]

Three newly created vice president positions centered around faculty development, research and business development demonstrate a continuation and expansion of Regenstrief's commitment to reshape how our vision is pursued. These positions will leverage our highly regarded strengths and forge stronger collaboration on all fronts.

Preventing transfers of long-stay nursing home patients to hospitals improves continuity of care and decreases costs to the healthcare system.

Despite a shortage of scientific studies on the long-term effectiveness of opioids, they are frequently perceived to be stronger, more powerful pain relievers than non-opioid alternatives. A new study investigates pre-existing perceptions about pain medications by individuals with chronic pain and how these perceptions relate to patients’ experiences with these medications.

A man goes down to the river and stares across the water. On the other side, there’s a road to the next town, where he can sell his crops and buy some seed. He thinks, Someone ought to build a bridge. He’s never built a bridge before. Neither have his friends. Looking around and shrugging, […]

INDIANAPOLIS – A newly published observational study from the Regenstrief Institute and Indiana University has found that increased levels of education, particularly for those who grew up in low-income rural areas, was significantly associated with the decrease in the risk of dementia and Alzheimer’s disease in older African Americans previously reported by the same research […]

INDIANAPOLIS – In the first nationwide study to measure the effect of the Medicare Annual Wellness Visit on early identification of cognitive impairment such as Alzheimer’s disease, researchers from the Indiana University Center for Aging Research, Regenstrief Institute and IU Center for Health Innovation and Implementation Science found the visit has only minimal impact on […]

INDIANAPOLIS – Controlling blood pressure with any of the commonly prescribed antihypertensive medications can prevent dementia in older African-Americans with hypertension according to a new study from Regenstrief Institute researchers.   African Americans are especially at risk of both hypertension and dementia. The new study provides substantial evidence of significant reduction of risk of onset […]

INDIANAPOLIS – Kurt Kroenke, MD, a Regenstrief Institute investigator and the director of the institute’s education and training programs, has been named the recipient of the Society of General Internal Medicine’s Robert J. Glaser award, the organization’s highest award. “The very fabric of modern primary care in the United States and internationally has been woven […]

Christopher M. Callahan, MD, the founding director of the Indiana University Center for Aging Research and a Regenstrief Institute investigator, will serve as the Society of General Internal Medicine’s Distinguished Professor of Geriatrics at the organization‘s 2018 annual meeting in Denver from April 11 to 14. Over nearly three decades, Dr. Callahan has developed, tested […]

INDIANAPOLIS – According to a survey by Pew Research, nearly two-thirds of adults in the U.S. collect their own data on at least one health indicator through the use of tracking devices and apps, and it is estimated by industry analysts that over 30 million Americans have access to their sleep data. While many patients […]

Agile Implementation: Transforming the healthcare delivery system from Health Care 1.0 to Health Care 2.0 INDIANAPOLIS — Scientist-clinicians from the Indiana University Center for Health Innovation and Implementation Science, Regenstrief Institute and IU Center for Aging Research have designed, developed and implemented an effective, simple new methodology — Agile Implementation — for faster, efficient, scalable, […]

INDIANAPOLIS – Treating acutely ill nursing home residents in place and avoiding hospitalizations when possible is better for their health and for the healthcare system. Common diagnoses, such as heart failure or urinary tract infection, are often used to classify whether a hospitalization of a nursing home resident was “potentially avoidable.” But predicting ahead of […]

Use of hospice has exploded over the past decades with approximately half of those who die while enrolled in Medicare receiving hospice care. A new study from the Indiana University Center for Aging Research and the Regenstrief Institute compares the quality of hospice services provided for patients living at home, in assisted living facility and […]

INDIANAPOLIS – The first national study of the quality of the care offered by the Veterans Health Administration to patients following a transient ischemic attack (known as a TIA and sometimes called a ministroke) reports that the largest healthcare system in the United States is providing good quality care but also identifies targets for improvement […]

  INDIANAPOLIS – How patients and their healthcare providers communicate with one another outside the clinic or doctor’s office is changing. But how do patients and their physicians feel about email, cell phone and text interactions? A new study led by Joy L. Lee, PhD of the Regenstrief Institute’s Center for Health Services Research compares […]

INDIANAPOLIS — Are patients less likely to be hospitalized if emergency departments have access to their complete medical record via health information exchange? Regenstrief Institute scientists are conducting the first study of health information exchange use over multiple years to evaluate whether it improves patient outcomes in emergency departments. The innovative work will measure actual use […]

INDIANAPOLIS — Family caregivers of individuals who have cognitive disorders are faced with complex and stressful challenges for which they are often unprepared and unsupported. Health services researcher Nicole Fowler, PhD, MHSA of the Indiana University Center Aging Research, Regenstrief Institute and IU Center for Health Innovation and Implementation Science, and colleagues have received grants […]

INDIANAPOLIS – Nearly half of the 13 million older adults hospitalized annually in the United States are unable to make their own medical decisions and rely on surrogates, usually close family members, to make decisions for them. However little is known about how these surrogates respond to the demands put upon them. A new study […]

INDIANAPOLIS — The initial phase of OPTIMISTIC, an innovative program developed and implemented by clinician-researchers from the Indiana University Center for Aging Research and partners to decrease avoidable hospitalizations of long-stay nursing facility residents, reduced these events a striking 33 percent, according to an independent evaluation prepared at the request of the Center for Medicare […]

INDIANAPOLIS — A growing number of individuals of all ages are surviving intensive care unit hospitalization, however their mental and physical health problems persist. A new study from Regenstrief Institute and Indiana University researchers reports that a care model they originally developed for older adults with dementia could benefit ICU survivors of all ages. ICU […]

INDIANAPOLIS — Communication between patients and clinicians that is patient-centered, taking into account patient concerns and preferences has important implications for patient safety. Involving the patient is critical for improving medication safety according to Regenstrief Institute researcher and Indiana University School of Medicine assistant professor of medicine Joy L. Lee, PhD, corresponding author of “Towards […]

INDIANAPOLIS — The National Institute on Aging has awarded two researchers at IUPUI a $400,000 grant to work with nursing homes to design a real-world program to provide systematic, high-quality advance care planning for nursing home patients with Alzheimer’s disease and related dementias. The initial grant will be followed by a $3 million second phase […]

INDIANAPOLIS — Regenstrief Institute investigator Daniel J. Vreeman, DPT, director of LOINC and Health Data Standards in the Regenstrief Center for Biomedical Informatics and Regenstrief-McDonald Scholar in Data Standards at Indiana University School of Medicine, has been elected as a fellow of the American College of Medical Informatics. He joins a select group of individuals […]

INDIANAPOLIS – Indiana University, the Regenstrief Institute and Indianapolis-based technology company LifeOmic have announced a first-of-its-kind collaboration to advance the development of precision medicine, a personalized approach to disease treatment and prevention. Under terms of the agreement, LifeOmic receives a blanket license to a broad range of intellectual property owned by IU and Regenstrief as […]

Indianapolis, Indiana, September 13th, 2017 – The Indiana Chapter of HIMSS announces the Indiana Medicaid Data Challenge, to be held at Regenstrief Institute in downtown Indianapolis on Saturday, October 21st, 2017 from 8AM to 5PM. Teams of participants will compete to demonstrate innovative visualization and analysis of Medicaid healthcare information that is being de-identified and […]

Following three successful years of formative work, the Center for Cancer Population Analytics and Patient-Centered Informatics has been named an IUPUI Signature Center. Led by Indiana University Associate Professor of Medicine and Regenstrief Research Scientist David Haggstrom, MD, MAS, the center’s scientific core – representing productive collaborations with the IU Schools of Medicine, Informatics and […]

INDIANAPOLIS – Intensive care unit survivors, growing in number as clinicians and medical technology save more lives, are psychologically as well as medically fragile. The first study to examine antidepressant use and depressive symptoms after an ICU stay, has found that even if prescribed antidepressants, a significant percentage–about a third–had symptoms of depression at the […]

INDIANAPOLIS – Matching patients to their medical records from multiple health care providers is critical to medical care, but can be challenging to accomplish because their records can be incomplete or inaccurate, and patients often share similar names. How, for example, to match medical records to the correct “John Jones” or “Maria Garcia” from their […]

Alexia Torke, MD was appointed associate division chief for the Division of General Internal Medicine and Geriatrics for the Indiana University School of Medicine effective July 1, 2017. The announcement was made by Greg Sachs, MD, chief of the Division of General Internal Medicine and Geriatrics. Torke will be assuming responsibility to assist the Division […]

INDIANAPOLIS – A visit by a home health worker, such as a nurse or physical therapist, within a week of an older adult’s discharge from a skilled nursing facility appears to lower the risk of hospital readmission within 30 days by nearly half according to a new Indiana University Center for Aging Research and the Regenstrief […]

Regenstrief & IU to offer unique public and population health informatics training program INDIANAPOLIS — The Regenstrief Institute, internationally recognized for its research and training programs in clinical informatics, will now train researchers in the increasingly important fields of public and population health informatics. The unique new program, in collaboration with Indiana University School of […]

Researchers from the Indiana University Center for Aging Research and the Regenstrief Institute are developing and testing the nation’s first program to deliver via telemedicine specially designed cognitive training and physical exercise programs to the homes of hospital intensive care survivors who have experienced delirium while in the ICU. Delirium is an acute brain failure […]

INDIANAPOLIS – An estimated 1.4 million Americans over age 50 are hospitalized for severe injuries annually–most often due to motor vehicle crashes or falls. The majority have the potential for full recovery from the trauma, yet a large percentage do not reach their full potential. With the support of a new $2.5 million, five-year award […]

INDIANAPOLIS – Shaun Grannis, MD, MS, FAAFP, Regenstrief Institute investigator and associate professor of Family Medicine at the Indiana University School of Medicine, has been appointed director of the Regenstrief Institute Center for Biomedical Informatics (CBMI). Dr. Grannis, an internationally recognized expert in informatics and biosurveillance, was named a Regenstrief Institute investigator in July 2004 and has been serving as interim director since January 2016.

INDIANAPOLIS – NiCole Keith, PhD, FACSM, was promoted to acting associate dean for Indiana University-Purdue University Indianapolis’ School of Physical Education and Tourism Management. Keith moves into this position while Rafael E. Bahamonde, PhD, FACSM, serves as interim dean during the search for a permanent replacement to outgoing dean James "Jay" Gladden, PhD who began his position as dean of University College and associate vice chancellor for undergraduate education on February 1st.

Developed as part of AMA’s initiative to create the medical school of the future, new training platform will help ensure physicians and other health care professionals learn how to use EHRs to deliver patient care in modern health system CHICAGO – With the majority of today’s physicians graduating from medical school without comprehensive training using […]

INDIANAPOLIS — Researchers from the Indiana University Center for Aging Research and the Regenstrief Institute have performed the first study conducted in the United States under real-world conditions comparing patient adherence and tolerability to a class of drugs known as cholinesterase inhibitors. Although there are no known cures for Alzheimer’s disease or other dementias, drugs […]

INDIANAPOLIS — A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found only minimal differences in the intensity of hospice services provided in nursing homes as compared to hospice services provided to patients in assisted living facilities or their homes. However the mix of services did vary by […]

INDIANAPOLIS — Millions of intensive care unit patients in the United States experience delirium, an acute brain failure resulting in confusion and long-term memory problems. Researchers from the Indiana University Center for Aging Research have developed and validated a novel easy-to-administer tool to score and track delirium severity in the ICU, enabling clinicians to make […]

INDIANAPOLIS – The OPTIMISTIC model of care, an innovative program developed and implemented by clinician-researchers to prevent unnecessary hospitalizations of long-stay nursing home residents reduced hospitalizations for diagnoses considered potentially avoidable by nearly 40 percent and total hospitalizations by 25 percent according to a study published in the March issue of the journal Health Affairs. […]

INDIANAPOLIS – The Regenstrief-McDonald Chair in Data Standards has been established and endowed by the Regenstrief Foundation at Indiana University School of Medicine. The new position honors and perpetuates the legacies of two giants who have focused on improving human health — Sam Regenstrief, the namesake of the foundation and of the internationally respected Regenstrief […]

INDIANAPOLIS — Regenstrief Institute investigator John T. Finnell, MD, MSc, an associate professor of clinical emergency medicine at the Indiana University School of Medicine, has been inducted as a fellow of the American College of Medical Informatics. He joins a select elected group of individuals who have made significant and sustained contributions to the field […]

INDIANAPOLIS — The Critical Care Recovery Center, or CCRC, model developed and tested by the Indiana University Center for Aging Research, the Regenstrief Institute and Eskenazi Health has received the 2017 THRIVE Innovation Award from the Society of Critical Care Medicine. The honor recognizes the nation’s first collaborative care concept targeting the extensive cognitive, physical […]

Partnership commercializes validated research and world-renowned expertise to extract clinical insights from text records ORLANDO, Fla., Feb. 21, 2017 /PRNewswire/ — From the floor of the HIMSS17 Conference & Exhibition in Orlando, Health Catalyst and the Regenstrief Institute announced today an agreement to bring Regenstrief’s artificial intelligence-powered text analytics technology out of the lab and into healthcare […]

INDIANAPOLIS — Indiana University Center for Health Innovation and Implementation Science Chief Operating Officer Nadia Nguyen Adams, MHA is working to empower doctors, nurses and other clinicians with the information, services, and support needed to provide the best care, at a lower cost, for better health outcomes for over 10 million residents of Indiana, Illinois, […]

INDIANAPOLIS — Two million of the five million Americans admitted to intensive care units annually have or develop acute respiratory failure, predisposing them to long-term cognitive, functional and psychological impairments collectively known as post-intensive care syndrome. A new $3.2 million grant from the National Heart, Lung, and Blood Institute funds the development and evaluation of […]

INDIANAPOLIS – Online patient video journals or blogs–called vlogs–chronicling the good, the bad and the ugly of a specific medical condition can help both physicians and their patients, says Regenstrief Institute and Indiana University Center for Health Services and Outcomes Research investigator Joy L. Lee, PhD, corresponding author of “Seeing is Engaging: Vlogs as a […]

INDIANAPOLIS — Indiana University’s OPTIMISTIC study has added an additional 25 facilities across Indiana as it expands its efforts to improve the health and health care of long-term nursing home residents. Over the next four years, the 19 central Indiana nursing homes that participated in OPTIMISTIC’s initial phase plus the 25 additional nursing homes from […]

INDIANAPOLIS – Patients who are activated — meaning they have the knowledge, skills and confidence to manage their health and health care — have better health outcomes. A new study provides evidence that male and female African-American veterans receiving outpatient mental health services are not as activated as White veterans. In addition to demonstrating an […]

INDIANAPOLIS — Nearly 20 percent of older Americans experience depression and the highest rate of suicide is among older adult Caucasian males. Despite the anticipated growth of mental health needs as the U.S. population ages, there is only one geriatric psychiatrist for every 23,000 older Americans. By 2030, there will only be one geriatric psychiatrist […]

INDIANAPOLIS – In the first study to compare the results of cognitive training by body mass index (BMI) category, scientists from the Indiana University Center for Aging Research found that memory training provided only one-third the benefit to older adults with obesity than the benefit it provided to older adults without obesity. To determine responsiveness […]

Anticholinergic medications, a class of drugs commonly used by older adults, are linked to an increased rate of emergency department and hospital utilization in the United States, according to a study of community-dwelling Americans age 65 and older by the Center for Aging Research, Indiana University Center for Health Innovation and Implementation Science, and Regenstrief […]

INDIANAPOLIS — Peter J. Embi, MD, MS, who joins the Regenstrief Institute as president and CEO on December 15, has been selected as the chair-elect of the board of directors of the American Medical Informatics Association, the largest international professional biomedical and health informatics association. The four-year term includes a one-year term as chair-elect, two […]

INDIANAPOLIS – In the first study to investigate whether two years of in-home occupational therapy might help those with Alzheimer’s disease delay the loss of their physical function, researchers from the Indiana Center for Aging Research and the Regenstrief Institute have found that occupational therapy tailored to the individual patient’s needs did not delay the […]

INDIANAPOLIS – It can be challenging to determine whether the medical care provided in a hospital or nursing home is consistent with the preferences of the patient and family as indicated in the patient’s advance planning documents. Currently nearly a quarter of hospitalized older Americans are unable to make end-of-life decisions for themselves. In the […]

  INDIANAPOLIS — Burke Mamlin, MD, and Paul Biondich, MD, of the Regenstrief Institute and Indiana University School of Medicine will be honored on November 12 with the 2016 Donald A.B. Lindberg Award for Innovation in Informatics. The award will be presented by the American Medical Informatics Association (AMIA), the largest international professional biomedical informatics […]

Decision makers in low- and middle-income countries know the value of health information exchange (HIE). Unfortunately these nations may lack access to resources that accelerate the establishment of policies and procedures needed to support it.  A new framework published by the Regenstrief Institute aims to cull together HIE experience and implementation knowledge to assist HIE decision-makers […]

INDIANAPOLIS — The Aging Brain Care Medical Home, a novel brain-focused population health management program implemented in the homes of older adults, lowered depression severity by more than 50 percent over six months according to a new study from the Regenstrief Institute, Indiana University Center for Aging Research, IU Center for Health Innovation and Implementation […]

INDIANAPOLIS — The goal of advance care planning is to ensure that the health care an individual receives is consistent with his or her values and preferences. New research shows the critical need for advance care planning and highlights the challenges that healthcare institutions — especially nursing homes — face in supporting high quality advance […]

INDIANAPOLIS — Have a dental emergency? Your smartphone may be able to help you avoid an unnecessary trip to the hospital. A team mentored by Thankam Thyvalikakath, DMD, PhD, now of the Indiana University School of Dentistry and of the Regenstrief Institute, has developed and tested a novel mobile application enabling smartphones to capture and […]

INDIANAPOLIS — More than 13 million older adults are admitted to hospitals annually in the United States. Nearly a quarter need to have all decisions made for them by a family member, and almost half need help from family to make some decisions. Clinician-researchers from the Indiana University Center for Aging Research and the Regenstrief Institute […]

The Regenstrief Institute, an internationally respected leader in health services, informatics and aging research, recently hosted the 2016 Department of Veterans Affairs Health Services Research and Development national field-based meeting on informatics research. Sixty-two invited participants from across the United States gathered Sept. 29-30 at the institute’s new headquarters to shape the next decade of […]

INDIANAPOLIS – Transfers of nursing home residents to and from the hospital frequently expose these frail, older adults to medication errors and poor follow-up care resulting in near or serious harm to one in four nationwide. Research conducted as part of the OPTIMISTIC study, an innovative program developed and implemented at a growing number of […]

INDIANAPOLIS — Debra K. Litzelman, MA, MD, MACP, has been awarded Mastership in the American College of Physicians (ACP), the national organization of internists. Dr. Litzelman is the D. Craig Brater Professor of Global Health Education and Professor of Medicine at the Indiana University School of Medicine (IUSM), a Senior Research Scientist at the Regenstrief […]

Imperiale named IU’s first Lawrence Lumeng Professor in Gastroenterology and Hepatology INDIANAPOLIS — Regenstrief Institute investigator Thomas F. Imperiale, M.D., has been named the inaugural Lawrence Lumeng Professor in Gastroenterology and Hepatology at Indiana University School of Medicine. Dr. Imperiale is an internationally respected health services researcher and a clinical gastroenterologist. Dr. Imperiale’s research, which […]

If you are rushed to a hospital in an emergency, is your complete medical record available to those caring for you? Will they know all medications you have been prescribed and whether you are taking them as directed? Does your primary care physician know your complete medical history?

July 21, 2016 INDIANAPOLIS — While the incidence of colon cancer has been declining in individuals 50 years old and older in the United States, it is steadily rising in those under age 50. With funding from the U.S. Department of Veterans Affairs, Thomas F. Imperiale, M.D., a VA and Regenstrief Institute clinician-researcher, is developing […]

June 30, 2016 INDIANAPOLIS — LOINC, the world’s most commonly used universal code system for identifying medical test results, observations and other clinical measurements, has announced the inaugural recipients of the LOINC Award for Distinguished Contributions. The new award honors individuals whose work advances the interoperability that ensures that medical data can be recorded, electronically […]

June 23, 2016 INDIANAPOLIS — A new grant to the Indiana University Center for Aging Research from the National Institute on Aging funds the first study to assess the potential benefits and harms to family members of early dementia screening of older adults. The Effects on Families of older adults Experiencing Cognitive Testing (EFECT) study […]

June 14, 2016 INDIANAPOLIS — The first study to evaluate the relationship between race and intensive care unit delirium has found that African-American ICU patients age 18 to 50 are less susceptible to delirium than similarly aged Caucasians or than either African-American or Caucasian ICU patients age 50 or older. Delirium is a state of […]

June 6, 2016 INDIANAPOLIS — More than 53 million Americans age 50 and older, primarily women, have osteoporosis or are at high risk for the condition due to low bone density. A recent study of oral bisphosphonates, the most commonly prescribed osteoporosis treatment, found that approximately a third of women prescribed these drugs continue to […]

INDIANAPOLIS — Christopher Callahan, M.D., the founding director of the Indiana University Center for Aging Research, a Regenstrief Institute investigator and the Cornelius and Yvonne Pettinga Professor of Medicine at Indiana University School of Medicine, has been named the 2016 recipient of the American Geriatrics Society’s prestigious Edward Henderson Award. Dr. Callahan is an internationally […]

May 5, 2016                                                                                             INDIANAPOLIS — Use of hospice services does […]

April 21, 2016 INDIANAPOLIS — Machine learning has come of age in public health reporting according to researchers from the Regenstrief Institute and Indiana University School of Informatics and Computing at Indiana University-Purdue University Indianapolis. They have found that existing algorithms and open source machine learning tools were as good as, or better than, human […]

April 19, 2016 INDIANAPOLIS — A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage […]

April 12, 2016 INDIANAPOLIS — The National Alzheimer’s Project Act (NAPA) was signed into law in 2011.  Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support. Now, the Alzheimer’s Association National Plan […]

April 7, 2016 INDIANAPOLIS — A new study from the Indiana University School of Medicine and the Regenstrief Institute has found that person-centered dementia care, which involves both patients and their caregivers, can be effectively provided by an engaged low-cost workforce — care coordinator assistants. Under the close supervision of clinical professionals, the care coordinator […]

March 28, 2016 INDIANAPOLIS — With the announcement of an additional $16.9 million for a total of more than $30 million of Centers for Medicare and Medicaid Services funding since 2012, Indiana University’s OPTIMISTIC project commences the second phase of an innovative endeavor with a goal of improving the health and health care of long-term […]

The amount of information about you, your habits and your health that is stored by various places you visit might surprise you. Whether it’s the grocery store, gym, bike-share service, family doctor or pharmacy, databases around town could offer you a remarkably clear picture of your personal health — IF they were unified. Could Indy […]

February 29, 2016 INDIANAPOLIS — Expectations for health information technology abound. A paper from the Regenstrief Institute takes a sweeping look at a variety of categories of health IT including electronic medical records; health information exchange; telemedicine; patient portals and personal health records; mobile devices, wearable sensors and monitors; and social media. The authors evaluate […]

February 8, 2016 INDIANAPOLIS — Once again, Indiana is a leader in life-saving technology. On Tuesday, January 26, a unique workshop brought together professionals from all aspects of health care to discuss “Indiana’s Opportunities to Lead in Digital Health.” Presenters Dr. Nir Menachemi from the Indiana University Richard M. Fairbanks School of Public Health and […]

January 28, 2016 INDIANAPOLIS — The first study to investigate the effects of cognitive training on the cognitive functioning of older adults by education level has found that individuals with fewer than 12 years of schooling benefit more from cognitive training than their more highly educated counterparts. While the effects of reasoning and memory training […]

January 27, 2016 INDIANAPOLIS — With support from a three-year $1.2 million grant from the National Institute of Dental and Craniofacial Research’s National Dental Practice-Based Research Network, researchers from the Regenstrief Institute and the Indiana University School of Dentistry will conduct an analysis of electronic dental records of patients treated by community dentists across the United States […]

January 21, 2016 INDIANAPOLIS — Might it be possible to identify and then reach out to help medical students whose actions may put them at risk of lapses in professionalism in medical school and beyond? Professionalism lapses are the most common cause for disciplinary action against practicing physicians. A new study from the Indiana University […]